Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666185 | 0.91 | P2RX1 (0.51) | PARK7P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL665474 | 0.88 | PARK7 (0.49) | PARK7P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL666669 | 0.88 | PARK7 (0.53) | PARK7P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL666528 | 0.86 | PARK7 (0.50) | PARK7PLAUF2F10PLG | |
| Dehydroxymethylepoxyquinomicin SCHEMBL14504317 | 0.84 | PARK7 (0.54) | PARK7P2RX1P2RX4P2RX7KCNMA1 | |
| Dehydroxymethylepoxyquinomicin SCHEMBL14491796 | 0.84 | PARK7 (0.54) | PARK7P2RX1P2RX4P2RX7KCNMA1 | |
| Dehydroxymethylepoxyquinomicin SCHEMBL1669417 | 0.84 | PARK7 (0.54) | PARK7P2RX1P2RX4P2RX7KCNMA1 | |
| Dehydroxymethylepoxyquinomicin SCHEMBL1671089 | 0.84 | PARK7 (0.54) | PARK7P2RX1P2RX4P2RX7KCNMA1 | |
| SCHEMBL116427 | 0.83 | PARK7 (0.48) | PARK7P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL169409 | 0.83 | PARK7 (0.48) | PARK7KLKB1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046357-A1 | Benzamide and Napthamide Derivatives Inhibiting Nuclear Factor-Kappa (B) - (NK-kB) | PROFECTUS BIOSCIENCES, INC. (US) | 2012-02-23 | — | — | US | claimed |
| US-20120046357-A1 | Benzamide and Napthamide Derivatives Inhibiting Nuclear Factor-Kappa (B) - (NK-kB) | PROFECTUS BIOSCIENCES, INC. (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046357-A1 | Benzamide and Napthamide Derivatives Inhibiting Nuclear Factor-Kappa (B) - (NK-kB) | NFKBIA, IKBKB, NFKB1 | PARK7 3384/4885P2RX1 855/4885P2RX4 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.