Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 6/20 | 0.61 |
| ▸ | DRD4 | P21917 | 6/20 | 0.61 |
| ▸ | DRD3 | P35462 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP4 | P49662 | 1/20 | 0.48 |
| ▸ | CASP5 | P51878 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653131 | 0.86 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1HSD17B10DRD2 | |
| SCHEMBL6655678 | 0.86 | KDM4E (0.65) | ALDH1A1KMT2AMEN1HSD17B10DRD2 | |
| SCHEMBL6652178 | 0.80 | MEN1 (0.64) | ALDH1A1KMT2AMEN1DRD2DRD4 | |
| SCHEMBL6653873 | 0.79 | POLB (0.68) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL7501987 | 0.76 | DRD2 (1.00) | ALDH1A1KMT2AMEN1HSD17B10DRD2 | |
| SCHEMBL6653746 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KMT2AHSD17B10KDM4EMAPT | |
| SCHEMBL6660468 | 0.75 | CASP1 (0.62) | ALDH1A1DRD4KDM4EGAAACHE | |
| Hydrochloric Acid SCHEMBL6651531 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KMT2AHSD17B10KDM4EMAPT | |
| SCHEMBL6649931 | 0.74 | MAPT (0.54) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| Hypochlorous Acid SCHEMBL6651534 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KMT2AHSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006110-B1 | DERIVATIVES OF ACYL-PIPERAZINIL-PYRIMIDINS, PREPARATION THEREOF AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-02-11 | — | — | EP | claimed |