Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.73 |
| ▸ | TUBB | P07437 | 5/20 | 0.73 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.73 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.73 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.73 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.73 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.73 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.73 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.73 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.73 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.73 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.73 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.73 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.73 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | KRAS | P01116 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819729 | 0.85 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9189645 | 0.84 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8500772 | 0.84 | CYP1A2 (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4823451 | 0.84 | CYP1A2 (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13240109 | 0.83 | TUBB1 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1308579 | 0.83 | TUBB4A (0.82) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL27888195 | 0.83 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1308241 | 0.83 | TUBB4A (0.73) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8626158 | 0.83 | ALDH1A1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2450750 | 0.82 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966424-B1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMA AS (DK) | 2004-06-23 | — | — | EP | disclosed |
| US-6313174-B1 | FOR THERAPY AND PROPHYLAXIS OF ASTHMA, ALLERGY, RHEUMATOID ARTHRITIS, SPONDYLOARTHRITIS, GOUT, ATHEROSCLEROSIS, CHRONIC INFLAMMATORY BOWEL DISEASE, PROLIFERATIVE AND INFLAMMATORY SKIN DISORDERS | Leo Pharmaceutical Products Ltd.A/S/ (Løvens kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-11-06 | — | — | US | disclosed |
| EP-0966424-A1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998032730-A1 | AMINOBENZOPHENONES AS INHIBITORS OF INTERLEUKIN AND TNF | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1998-07-30 | — | — | WO | disclosed |