Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | EIF4E | P06730 | 14/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649515 | 0.82 | MAPT (0.51) | EIF4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6651418 | 0.82 | C1S (0.54) | C1SEIF4EMAPTMEN1ALDH1A1 | |
| SCHEMBL6649196 | 0.80 | C1S (0.55) | C1SEIF4EMAPTMEN1ALDH1A1 | |
| SCHEMBL6651612 | 0.79 | C1S (0.54) | C1SEIF4EMAPTMEN1ALDH1A1 | |
| SCHEMBL6653028 | 0.78 | MAPT (0.50) | EIF4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6627829 | 0.76 | KDM4E (0.59) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6627147 | 0.76 | KDM4E (0.55) | ALDH1A1KMT2A | |
| SCHEMBL6649842 | 0.75 | CYP19A1 (0.52) | C1SMAPTALDH1A1KMT2A | |
| SCHEMBL6651514 | 0.74 | RAB9A (0.46) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6649421 | 0.74 | KDM4E (0.50) | MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432706-A2 | 3-PYRIDYL OR 4-ISOQUINOLINYL THIAZOLES AS C17,20 LYASE INHIBITORS | Bayer Pharmaceuticals Corporation (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003027085-A2 | 3-PYRIDYL OR 4-ISOQUINOLINYL THIAZOLES AS C17,20 LYASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |