Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL28318176 | 0.83 | POLB (0.46) | LMNAALDH1A1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL9800936 | 0.80 | LMNA (0.47) | LMNAHPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL16284295 | 0.80 | HTR2A (0.44) | LMNAHPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28208186 | 0.80 | ALDH1A1 (0.46) | LMNAHPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL27982520 | 0.80 | LMNA (0.43) | LMNAHPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL31303745 | 0.80 | ACHE (0.48) | LMNAHPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL13002995 | 0.78 | HPGD (0.46) | LMNAHPGDALDH1A1RAB9AGPR35 | |
| SCHEMBL24351653 | 0.76 | HPGD (0.44) | LMNAHPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL27796854 | 0.76 | HPGD (0.47) | LMNAHPGDALDH1A1RAB9AGPR35 | |
| SCHEMBL27920185 | 0.76 | ALDH1A1 (0.43) | LMNAHPGDALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104073045-A | Application of halogenated indole and derivatives thereof as marine antifouling agent | YANTAI INST COASTAL ZONE RES CAS | 2014-10-01 | — | — | CN | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| CN-108366979-A | Compounds and pharmaceutical compositions relating to ubiquitination-proteasome system | 台北医学大学 | 2018-08-03 | — | — | CN | disclosed |
| CN-107530395-A | Method for producing drug-related peptides | 康德生物医疗技术公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107108640-A | Synthesis of Bruton's Tyrosine Kinase Inhibitors | 药品循环有限责任公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-104073045-A | Application of halogenated indole and derivatives thereof as marine antifouling agent | YANTAI INST COASTAL ZONE RES CAS | 2014-10-01 | — | — | CN | disclosed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |