Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | DAO | P14920 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25681022 | 0.87 | ATAD2 (0.55) | LMNAPGRATAD2MEN1PABPC1 | |
| SCHEMBL19404420 | 0.85 | LMNA (0.53) | LMNAPGRATAD2MEN1PABPC1 | |
| SCHEMBL9786405 | 0.83 | S100B (0.58) | LMNAPGRMAOBS100BPDE2A | |
| SCHEMBL29859942 | 0.78 | LMNA (0.58) | LMNAPGRMEN1PABPC1KMT2A | |
| SCHEMBL2522765 | 0.78 | LMNA (0.58) | LMNAPGRMEN1PABPC1KMT2A | |
| Hydrochloric Acid SCHEMBL19384637 | 0.77 | LMNA (0.56) | LMNAPGRMAOBDAOADORA3 | |
| SCHEMBL1639030 | 0.77 | LMNA (0.56) | LMNAPGRMAOBDAOADORA3 | |
| SCHEMBL30692234 | 0.77 | LMNA (0.56) | LMNAPGRMAOBDAOADORA3 | |
| SCHEMBL13015581 | 0.73 | LMNA (0.56) | LMNAPGRKMT2AS100BPDE2A | |
| SCHEMBL31731190 | 0.72 | LMNA (0.54) | LMNAPGRMEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11222487-A | — | — | None | — | — | JP | disclosed |
| EP-1422267-A1 | New dyes based on 1,4,5,8-naphthalene tetracarboxylic dianhydride | CLARIANT INTERNATIONAL LTD. (CH) | 2004-05-26 | — | — | EP | disclosed |
| EP-0911332-B1 | Heterocyclic compounds | CLARIANT FINANCE BVI LTD (VG) | 2004-04-14 | — | — | EP | disclosed |
| US-6046335-A | Heterocyclic compounds | CLARIANT BVI (VG) | 2000-04-04 | — | — | US | disclosed |
| JP-H11222487-A | NEW HETEROCYCLIC COMPOUND | CLARIANT INTERNATL LTD | 1999-08-17 | — | — | JP | disclosed |
| EP-0911332-A1 | Heterocyclic compounds | Clariant Finance (BVI) Limited (VG) | 1999-04-28 | — | — | EP | disclosed |
| EP-0207483-B1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND INTERMEDIATES | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0257334-B1 | TRICYCLIC BENZOTRIAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1991-01-02 | — | — | EP | disclosed |
| US-4835167-A | Tricyclic benzotriazoles, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-30 | — | — | US | disclosed |
| US-4831032-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ISOTROPIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0257334-A2 | Tricyclic benzotriazoles, process for their preparation and medicaments | Roche Diagnostics GmbH (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0207483-A2 | Benzimidazoles, process for their preparation, medicaments containing them and intermediates | Roche Diagnostics GmbH (DE) | 1987-01-07 | — | — | EP | disclosed |
| US-4008225-A | Process for the manufacture of bis-azomethine metal complex colorants | CIBA-GEIGY CORPORATION (US) | 1977-02-15 | — | — | US | disclosed |
| US-3963708-A | Bis-azomethine metal complex colorants from hydroxycoumarin derivatives or hydroxychromone derivatives | CIBA-GEIGY CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |