Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153369 | 0.82 | HSP90AB1 (0.45) | — | |
| SCHEMBL8058952 | 0.73 | ADORA2B (0.40) | ADORA2AADORA1 | |
| SCHEMBL8781644 | 0.67 | ADORA2A (0.33) | ADORA2AADORA1 | |
| SCHEMBL4846999 | 0.66 | ADORA2A (0.42) | ADORA2AADORA1 | |
| SCHEMBL29601416 | 0.66 | ADORA2B (0.40) | ADORA2AADORA1 | |
| SCHEMBL9391801 | 0.66 | CSNK2A2 (0.44) | ADORA2AADORA1 | |
| SCHEMBL12311046 | 0.64 | ADORA2A (0.46) | ADORA2AADORA1 | |
| SCHEMBL7981147 | 0.64 | ADORA2B (0.42) | ADORA2AADORA1 | |
| SCHEMBL7968026 | 0.63 | ADORA2B (0.41) | ADORA2AADORA1 | |
| SCHEMBL7983989 | 0.63 | ADORA2A (0.35) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068210-B1 | PROCESS FOR THE PRODUCTION OF PURINE DERIVATIVES | NOVARTIS INT PHARM LTD (BM) | 2004-06-02 | — | — | EP | disclosed |
| US-6437125-B1 | REARRANGEMENT OF N-7 ALKYL GROUP TO THE N-9; PALLADIUM CATALYST AND A (DIPHENYLPHOSPHINO)ALKANE; PENCICLOVIR AND FAMCICLOVIR | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2002-08-20 | — | — | US | disclosed |
| EP-1068210-A2 | PROCESS FOR THE PRODUCTION OF PURINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051604-A2 | PROCESS FOR THE PRODUCTION OF PURINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1999-10-14 | — | — | WO | disclosed |