Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5921632 | 0.88 | MRGPRX4 (0.76) | ALOX5NR4A2MRGPRX4NR4A1NR4A3 | |
| Hydrochloric Acid SCHEMBL8380168 | 0.86 | MRGPRX4 (0.74) | ALOX5NR4A2MRGPRX4NR4A1NR4A3 | |
| SCHEMBL228290 | 0.85 | NR4A2 (0.74) | ALOX5NR4A2NR4A1NR4A3NPC1 | |
| SCHEMBL4258805 | 0.85 | MRGPRX4 (0.76) | ALOX5NR4A2MRGPRX4NR4A1NR4A3 | |
| SCHEMBL340107 | 0.84 | NR4A2 (0.77) | NR4A2MRGPRX4MAOBSRD5A2MEN1 | |
| SCHEMBL30412560 | 0.84 | NR4A2 (0.77) | NR4A2MRGPRX4MAOBSRD5A2MEN1 | |
| SCHEMBL3235219 | 0.84 | ALOX5 (0.61) | ALOX5NR4A2MRGPRX4NR4A1NR4A3 | |
| SCHEMBL10839211 | 0.82 | SMPD1 (0.74) | ALOX5MRGPRX4NPC1MAPT | |
| SCHEMBL1779167 | 0.82 | ALOX5 (0.59) | ALOX5NR4A2MRGPRX4NR4A1NR4A3 | |
| SCHEMBL8378881 | 0.81 | NR4A2 (0.68) | ALOX5NR4A2NR4A1NR4A3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5246953-A | — | — | None | — | — | JP | disclosed |
| CN-103627407-B | Cholesteric liquid crystal display 2,2 '-binaphthalene ester chiral dopant | 肯特显示器公司 | 2016-12-28 | — | — | CN | disclosed |
| CN-103339224-B | Tetraoxybiphenyl ester chiral dopant for cholesteric liquid crystal displays | KENT DISPLAYS INC | 2015-07-22 | — | — | CN | disclosed |
| US-9005478-B2 | 2,2′-binaphthalene ester chiral dopants for cholesteric liquid crystal displays | KENT DISPLAYS INCORPORATED (US) | 2015-04-14 | — | — | US | disclosed |
| US-20140117284-A1 | 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays | KENT STATE UNIVERSITY (US) | 2014-05-01 | — | — | US | disclosed |
| US-8709281-B2 | 2,2′-binaphthalene ester chiral dopants for cholesteric liquid crystal displays | KENT STATE UNIVERSITY (US) | 2014-04-29 | — | — | US | disclosed |
| CN-103627407-A | 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays | UNIV KENT STATE OHIO | 2014-03-12 | — | — | CN | disclosed |
| US-20140054498-A1 | 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays | KENT STATE UNIVERSITY (US) | 2014-02-27 | — | — | US | disclosed |
| CN-103339224-A | Tetraoxybiphenyl ester chiral dopant for cholesteric liquid crystal displays | KENT DISPLAYS INC | 2013-10-02 | — | — | CN | disclosed |
| US-20120273725-A1 | Tetraoxybiphenyl Ester Chiral Dopants for Cholesteric Liquid Crystal Displays | KENT STATE UNIVERSITY (US) | 2012-11-01 | — | — | US | disclosed |
| US-5891359-A | FLUOROTRIESTERAROMATIC COMPOUND FOR LIQUID CRYSTALS | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1999-04-06 | — | — | US | disclosed |
| US-5861108-A | IMPROVES HIGH SPEED RESPONSE PROPERTY AND TEMPERATURE DEPENDENCY OF THE RESPONSE TIME | MITSUI CHEMICALS, INC. (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0757032-A2 | Naphthalene compound, and liquid crystal composition and liquid crystal element using the same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5451339-A | Liquid crystal monomeric compound and liquid crystal polymer compound modified therewith | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1995-09-19 | — | — | US | disclosed |
| US-5443755-A | Optically active tetrahydropyrane derivatives, liquid crystal composition and liquid crystal device containing the same | KASHIMA OIL COMPANY (JP) | 1995-08-22 | — | — | US | disclosed |
| US-5364561-A | Diluent; optically tristable; electrooptics | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1994-11-15 | — | — | US | disclosed |
| US-5310500-A | Fluorinated naphthalenecarboxylic acid ester derivatives; electrooptics | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0571276-A1 | Liquid crystal monomeric compound and liquid crystal polymer compound modified therewith | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1993-11-24 | — | — | EP | disclosed |
| JP-H05246953-A | LIQUID CRYSTAL COMPOUND | SHOWA SHELL SEKIYU KK | 1993-09-24 | — | — | JP | disclosed |
| EP-0518636-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140054498-A1 | 2,2'-Binaphthalene Ester Chiral Dopants for Cholesteric Liquid Crystal Displays | DHCR7, NR1H4, CYP46A1 | ALOX5 1166/4885NR4A2 125/4885MRGPRX4 3934/4885 |
| US-20120273725-A1 | Tetraoxybiphenyl Ester Chiral Dopants for Cholesteric Liquid Crystal Displays | DHCR7, CYP7A1, CCR7 | ALOX5 1057/4885NR4A2 110/4885MRGPRX4 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.