SCHEMBL6652236

SCHEMBL6652236

CCCCCCCCOC(=O)c1ccc2cc(O)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.63
TSHR P16473 2/20 0.63
LMNA P02545 1/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2D6 P10635 1/20 0.63
MAPK1 P28482 1/20 0.63
CYP2C19 P33261 1/20 0.63
NR1H2 P55055 1/20 0.63
RNASEL Q05823 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
ALDH1A1 P00352 2/20 0.58
NPC1 O15118 1/20 0.58
MAPT P10636 1/20 0.58
RAB9A P51151 1/20 0.58
AKR1C4 P17516 1/20 0.58
AKR1C3 P42330 1/20 0.58
AKR1C2 P52895 1/20 0.58
AKR1C1 Q04828 1/20 0.58
STS P08842 5/20 0.54
CHRM1 P11229 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4945610 1.00 ESR1 (0.63) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL6650964 1.00 ESR1 (0.63) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL6652345 1.00 ESR1 (0.63) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL6648699 0.99 ESR1 (0.65) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL6654130 0.94 ESR1 (0.71) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL9458337 0.93 ALDH1A1 (0.67) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL9458677 0.93 ALDH1A1 (0.67) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL4853372 0.93 ALDH1A1 (0.67) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL9458309 0.93 ALDH1A1 (0.67) ESR1TSHRLMNACYP1A2CYP2D6
SCHEMBL16632600 0.93 ALDH1A1 (0.67) ESR1TSHRLMNACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104768914-A Method for producing 6,6'-(ethylenedioxy)di-2-naphthoic acid diester TEIJIN LTD 2015-07-08 CN disclosed
EP-1120399-B1 Naphthalene compound, and liquid crystal composition and liquid crystal element using the same MITSUI CHEMICALS INC (JP) 2004-06-09 EP disclosed
EP-1120400-B1 Naphtahlene compound, and liquid crystal composition and liquid crystal element using the same MITSUI CHEMICALS INC (JP) 2003-09-24 EP disclosed
EP-0757032-B1 Naphthalene compound, and liquid crystal composition and liquid crystal element using the same MITSUI CHEMICALS INC (JP) 2001-12-12 EP disclosed
EP-1120399-A1 Naphthalene compound, and liquid crystal composition and liquid crystal element using the same Mitsui Chemicals, Inc. (JP) 2001-08-01 EP disclosed
EP-1120400-A1 Naphtahlene compound, and liquid crystal composition and liquid crystal element using the same Mitsui Chemicals, Inc. (JP) 2001-08-01 EP disclosed
US-5861108-A IMPROVES HIGH SPEED RESPONSE PROPERTY AND TEMPERATURE DEPENDENCY OF THE RESPONSE TIME MITSUI CHEMICALS, INC. (JP) 1999-01-19 US disclosed
EP-0757032-A2 Naphthalene compound, and liquid crystal composition and liquid crystal element using the same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-02-05 EP disclosed
US-5310500-A Fluorinated naphthalenecarboxylic acid ester derivatives; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1994-05-10 US disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
EP-0517498-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-09 EP disclosed