Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.71 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | STS | P08842 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648699 | 0.95 | ESR1 (0.65) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL4945610 | 0.94 | ESR1 (0.63) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL6652236 | 0.94 | ESR1 (0.63) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL6652345 | 0.94 | ESR1 (0.63) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL6650964 | 0.94 | ESR1 (0.63) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL709064 | 0.92 | ESR1 (0.67) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL6649099 | 0.92 | ESR1 (0.60) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL6651694 | 0.92 | ESR1 (0.60) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL5599708 | 0.91 | ESR1 (0.70) | ESR1TSHRLMNACYP1A2CYP2C19 | |
| SCHEMBL24517722 | 0.89 | HDAC6 (0.55) | ESR1TSHRLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159943-B | Method for synthesizing liquid crystal polyester by using rare earth catalyst | KINGFA TECHNOLOGY CO., LTD. (CN) | 2014-10-29 | — | — | CN | claimed |
| CN-103159943-B | Method for synthesizing liquid crystal polyester by using rare earth catalyst | KINGFA TECHNOLOGY CO., LTD. (CN) | 2014-10-29 | — | — | CN | disclosed |
| CN-103159943-A | Method for synthesizing liquid crystal polyester by using rare earth catalyst | KINGFA SCIENCE & TECHNOLOGY CO | 2013-06-19 | — | — | CN | disclosed |
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
| WO-2010122968-A1 | DIACYLETHYLENEDIAMINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
| EP-1120399-B1 | Naphthalene compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2004-06-09 | — | — | EP | disclosed |
| EP-1120400-B1 | Naphtahlene compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2003-09-24 | — | — | EP | disclosed |
| EP-0757032-B1 | Naphthalene compound, and liquid crystal composition and liquid crystal element using the same | MITSUI CHEMICALS INC (JP) | 2001-12-12 | — | — | EP | disclosed |
| EP-1120400-A1 | Naphtahlene compound, and liquid crystal composition and liquid crystal element using the same | Mitsui Chemicals, Inc. (JP) | 2001-08-01 | — | — | EP | disclosed |
| EP-1120399-A1 | Naphthalene compound, and liquid crystal composition and liquid crystal element using the same | Mitsui Chemicals, Inc. (JP) | 2001-08-01 | — | — | EP | disclosed |
| US-5298593-A | Polymerization of ester monomer, aromatic dicarboxylic acid, and oxyaromatic carboxylic acid | MITSUBISHI PETROCHEMICAL COMPANY, LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0520428-A2 | Method of producing thermotropic liquid crystalline polyester | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-12-30 | — | — | EP | disclosed |
| US-4937310-A | PROCESSABILITY AND HEAT RESISTANCE; POLYLACTONE COPOLYMERS OF P-HYDROXYBENZOIC ACID, 6-HYDROXYNAPHTHOIC ACID, RESORCINOL AND ISO-AND TEREPHTHALIC ACID | POLYPLASTICS CO., LTD. (JP) | 1990-06-26 | — | — | US | disclosed |
| US-4920197-A | Aromatic polyester | POLYPLASTICS CO., LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| US-4918154-A | COPOLYMER OF P-HYDROXYBENZOIC ACID, 6-HYDROXYL-2-NAPHTHOIC ACID, HYDROQUINONE, RESORCINOL, TEREPHTHALIC ACID, AND ISOPHTHALIC ACID; MELT PROCESSABILITY, HEAT RESISTANCE | POLYPLASTICS CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4910284-A | Aromatic polyester | POLYPLASTICS CO., LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0337727-A2 | Polyester resin exhibiting optical anisotropy in molten state and composition thereof | POLYPLASTICS CO. LTD. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0337729-A2 | Polyester resin exhibiting optical anisotropy in molten state and composition thereof | POLYPLASTICS CO. LTD. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0337728-A2 | Polyester resin exhibiting optical anisotropy in molten state and composition thereof | POLYPLASTICS CO. LTD. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0334619-A2 | Polyester resin exhibiting anisotropy in molten state and composition thereof | POLYPLASTICS CO. LTD. (JP) | 1989-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | ESR1 4281/4885TSHR 4189/4885LMNA 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.