Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 3/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647299 | 0.74 | DAO (0.52) | DAOPDE3BPDE3A | |
| SCHEMBL6471595 | 0.73 | DAO (0.39) | DAOPDE3BPDE3A | |
| SCHEMBL6649147 | 0.72 | PKM (0.45) | DAO | |
| SCHEMBL6650193 | 0.71 | DAO (0.43) | DAOPDE3BPDE3A | |
| SCHEMBL5215190 | 0.70 | DAO (0.49) | KMT2ADAOPDE3BPDE3A | |
| SCHEMBL6652310 | 0.68 | MAPK14 (0.47) | KMT2ADAOPDE3BPDE3A | |
| SCHEMBL359651 | 0.68 | KMT2A (0.69) | KMT2ABRD4CYP19A1 | |
| SCHEMBL4476585 | 0.67 | MAPK14 (0.51) | KMT2APARP14BRD4 | |
| SCHEMBL6648037 | 0.66 | THRA (0.41) | DAOPDE3BPDE3A | |
| SCHEMBL6648289 | 0.66 | MAOB (0.43) | DAOPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | Pharmacia Corporation (US) | 2004-12-29 | — | — | EP | claimed |
| WO-2003068230-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORPORATION (US) | 2003-08-21 | — | — | WO | claimed |