SCHEMBL6652432

SCHEMBL6652432

CC1=NN(c2ccc(S(=O)(=O)O)cc2)C(=O)C1=CC=Cc1ccc(N(C)C)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.73
KMT2A Q03164 9/20 0.73
MAPK1 P28482 7/20 0.73
MEN1 O00255 7/20 0.73
L3MBTL1 Q9Y468 5/20 0.73
HTT P42858 4/20 0.73
TDP1 Q9NUW8 3/20 0.73
PKM P14618 3/20 0.73
LMNA P02545 2/20 0.73
OPRK1 P41145 2/20 0.73
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA9 Q16790 1/20 0.61
ALDH1A1 P00352 7/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
POLB P06746 3/20 0.57
HPGD P15428 1/20 0.52
HSD17B10 Q99714 1/20 0.52
KAT8 Q9H7Z6 1/20 0.51
NPSR1 Q6W5P4 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317666 1.00 MAPT (0.73) MAPTKMT2AMAPK1MEN1L3MBTL1
Ammonia Solution, Strong SCHEMBL6653473 0.99 MAPT (0.72) MAPTKMT2AMAPK1MEN1L3MBTL1
SCHEMBL6654606 0.87 ALDH1A1 (0.66) MAPTKMT2AMAPK1MEN1L3MBTL1
SCHEMBL11674150 0.87 ALDH1A1 (0.66) MAPTKMT2AMAPK1MEN1L3MBTL1
SCHEMBL6654602 0.87 ALDH1A1 (0.66) MAPTKMT2AMAPK1MEN1L3MBTL1
SCHEMBL9875469 0.87 ALDH1A1 (0.66) MAPTKMT2AMAPK1MEN1L3MBTL1
SCHEMBL13528778 0.87 MAPT (0.58) MAPTKMT2AMAPK1MEN1L3MBTL1
SCHEMBL6655240 0.87 MAPT (0.58) MAPTKMT2AMAPK1MEN1L3MBTL1
Ammonia Solution, Strong SCHEMBL6655370 0.86 MAPT (0.57) MAPTKMT2AMAPK1MEN1L3MBTL1
Ammonia Solution, Strong SCHEMBL6656768 0.86 ALDH1A1 (0.65) MAPTKMT2AMAPK1MEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041953-B1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS WELLA AG (DE) 2004-07-07 EP claimed
US-6494923-B2 POLYMETHINE DYES, ESPECIALLY PYRAZOLONE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-12-17 US claimed
US-20020010969-A1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2002-01-31 US claimed
EP-1041953-A1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS Wella Aktiengesellschaft (DE) 2000-10-11 EP claimed
WO-1999059528-A2 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO claimed
EP-1041953-B1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS WELLA AG (DE) 2004-07-07 EP disclosed
US-6494923-B2 POLYMETHINE DYES, ESPECIALLY PYRAZOLONE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-12-17 US disclosed
US-20020010969-A1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2002-01-31 US disclosed
EP-1041953-A1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS Wella Aktiengesellschaft (DE) 2000-10-11 EP disclosed
WO-1999059528-A2 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed
US-5312721-A Bleachable antihalation system E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010969-A1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS KRT18, DSG1, SPTAN1 MAPT 1524/4885KMT2A 607/4885MAPK1 66/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.