Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348620 | 0.92 | PRCP (0.38) | ALDH1A1MAPK1PRCPKDRHPGD | |
| SCHEMBL319986 | 0.88 | PRCP (0.40) | ALDH1A1MAPK1PRCPKDRHPGD | |
| SCHEMBL28424140 | 0.87 | PRCP (0.39) | ALDH1A1MAPK1PRCPKDRHPGD | |
| Hydrochloric Acid SCHEMBL29771714 | 0.85 | PRCP (0.38) | ALDH1A1MAPK1PRCPKDRHPGD | |
| SCHEMBL6537096 | 0.85 | PRCP (0.34) | PRCP | |
| SCHEMBL28834278 | 0.82 | PRCP (0.36) | ALDH1A1MAPK1PRCPKDRHPGD | |
| SCHEMBL5350419 | 0.82 | PTGER1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2PRCP | |
| Propane SCHEMBL28734524 | 0.82 | HTR7 (0.37) | PRCP | |
| SCHEMBL29767639 | 0.82 | PRCP (0.38) | ALDH1A1MAPK1PRCPKDRHPGD | |
| SCHEMBL5356144 | 0.82 | PRCP (0.38) | ALDH1A1MAPK1PRCPKDRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421090-A2 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | Exxonmobil Chemical Patents Inc. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003002583-A2 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2003-01-09 | — | — | WO | disclosed |