SCHEMBL6652633

SCHEMBL6652633

O=C1OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccc3c(c21)O3

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 3/20 0.61
DHFR P00374 3/20 0.61
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
ALDH1A1 P00352 2/20 0.54
ALOX15 P16050 2/20 0.54
HSD17B10 Q99714 2/20 0.54
MAPT P10636 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
LMNA P02545 2/20 0.54
ESR1 P03372 1/20 0.54
TP53 P04637 1/20 0.54
CYP3A4 P08684 1/20 0.54
TSHR P16473 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
ESR2 Q92731 1/20 0.54
GPR55 Q9Y2T6 1/20 0.54
MMP2 P08253 1/20 0.45
MMP3 P08254 1/20 0.45
MMP9 P14780 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3378483 0.78 TYMS (0.61) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL6815170 0.77 TYMS (0.59) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL14481559 0.77 DHFR (0.59) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL14894102 0.77 DHFR (0.59) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL3607641 0.76 DHFR (1.00) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL1648480 0.75 TYMS (0.58) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL11443116 0.75 TYMS (0.58) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL9258357 0.75 TYMS (0.58) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL9395623 0.74 TYMS (0.65) TYMSDHFRMEN1KMT2AALDH1A1
SCHEMBL10889354 0.74 TYMS (0.56) TYMSDHFRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5258450-A Containing a polyorganosiloxane graft copolymer with an unsaturated carboxylic acid or anhydride; a polyisocyanate, polyoxazoline or polyepoxy compounds; and a filler MITSUBISHI RAYON CO., LTD. (JP) 1993-11-02 US claimed
EP-1039349-B1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK (JP) 2004-06-02 EP disclosed
US-6335133-B1 STABILITY, FOR FORMING IMAGES CANON KABUSHIKI KAISHA (JP) 2002-01-01 US disclosed
EP-1039349-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2000-09-27 EP disclosed
EP-0380108-B1 Polyarylene sulfide resin composition MITSUBISHI RAYON CO (JP) 1994-04-27 EP disclosed
US-5284917-A Methacrylimide-containing polymer blended with a polyester or polyamide; multifunctional epoxy, isocyanate or oxazoline compound MITSUBISHI RAYON CO., LTD. (JP) 1994-02-08 US disclosed
US-5258450-A Containing a polyorganosiloxane graft copolymer with an unsaturated carboxylic acid or anhydride; a polyisocyanate, polyoxazoline or polyepoxy compounds; and a filler MITSUBISHI RAYON CO., LTD. (JP) 1993-11-02 US disclosed
US-5094930-A ELECTROPHOTOGRAPHIC PHOTORECEPTOR KONICA CORPORATION (JP) 1992-03-10 US disclosed
EP-0380108-A2 Polyarylene sulfide resin composition MITSUBISHI RAYON CO., LTD. (JP) 1990-08-01 EP disclosed