Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194071 | 0.77 | CYP1A2 (0.49) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL5901254 | 0.75 | RAB9A (0.39) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL16660490 | 0.75 | ADRB2 (0.51) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL5901235 | 0.74 | MAPT (0.44) | KDM4ELMNAMAPTRAB9ANPC1 | |
| SCHEMBL14301805 | 0.72 | CYP1A2 (0.44) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL2268387 | 0.72 | OPRK1 (0.37) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 | |
| Bromide SCHEMBL5315408 | 0.71 | OPRK1 (0.36) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL18286705 | 0.69 | CYP1A2 (0.39) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL17561707 | 0.69 | CYP1A2 (0.42) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL16806045 | 0.69 | CYP1A2 (0.39) | CYP1A2CYP2C19CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |