Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3015878 | 0.97 | CYP2A6 (0.42) | CYP2A6CES2CES1ALOX15CA2 | |
| SCHEMBL6691577 | 0.97 | CYP2A6 (0.42) | CYP2A6CES2CES1ALOX15CA2 | |
| SCHEMBL6691571 | 0.97 | CYP2A6 (0.42) | CYP2A6CES2CES1ALOX15CA2 | |
| Water SCHEMBL3165300 | 0.95 | CYP2A6 (0.40) | CYP2A6CES2CES1ALOX15CA2 | |
| SCHEMBL9153089 | 0.85 | CA1 (0.36) | CA2CA1ALDH1A1 | |
| SCHEMBL11859127 | 0.82 | CA1 (0.33) | CA2CA1 | |
| SCHEMBL7961201 | 0.77 | CYP2A6 (0.46) | CYP2A6ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10606718 | 0.77 | ESR1 (0.35) | — | |
| SCHEMBL5632527 | 0.75 | CYP2A6 (0.45) | CYP2A6ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4457914 | 0.74 | CA3 (0.47) | ALOX15CA2CA1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116574038-B | Preparation method of N-aryl sulfonamide derivative | 安阳师范学院 | 2025-04-18 | — | — | CN | claimed |
| CN-115403494-B | Method for synthesizing beta-hydroxy sulfone derivative by oxygen-initiated olefin double-functionalization under mild condition | 湘潭大学 | 2024-01-02 | — | — | CN | claimed |
| CN-116574038-A | Preparation method of N-aryl sulfonamide derivative | 安阳师范学院 | 2023-08-11 | — | — | CN | claimed |
| US-4039334-A | ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-02 | — | — | US | claimed |
| US-20250326721-A1 | SSAO INHIBITORS AND USE THEREOF | ECCOGENE INC (US) | 2025-10-23 | — | — | US | disclosed |
| CN-116574038-B | Preparation method of N-aryl sulfonamide derivative | 安阳师范学院 | 2025-04-18 | — | — | CN | disclosed |
| CN-114901649-B | SSAO inhibitors and uses thereof | 诚益生物(美国)公司 | 2024-07-23 | — | — | CN | disclosed |
| US-20240190821-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES INC (US) | 2024-06-13 | — | — | US | disclosed |
| US-11964942-B2 | SSAO inhibitors and use thereof | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2024-04-23 | — | — | US | disclosed |
| CN-117623838-A | Chiral sulfoxide ester compound and preparation method thereof | 贵州大学 | 2024-03-01 | — | — | CN | disclosed |
| US-11744896-B2 | Compositions, use, and method for CDK2-PROTACs for cancer therapy and hearing loss | CREIGHTON UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
| US-11744896-B2 | Compositions, use, and method for CDK2-PROTACs for cancer therapy and hearing loss | CREIGHTON UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
| EP-0107622-A1 | Benzodioxole derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |
| EP-0101408-A1 | Monoazo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-02-22 | — | — | EP | disclosed |
| EP-0005251-B1 | PROCESS FOR THE PREPARATION OF SULFINATES OF 4,4'-DIAMINOBENZHYDROL AND OF ITS SUBSTITUTED PRODUCTS, AND COPYING PAPER CONTAINING THESE COMPOUNDS | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
| EP-0005475-A1 | Process for the preparation of 4,4'-diaminobenzhydrol and its substitution products | BAYER AG (DE) | 1979-11-28 | — | — | EP | disclosed |
| EP-0005251-A2 | Process for the preparation of sulfinates of 4,4'-diaminobenzhydrol and of its substituted products, and copying paper containing these compounds | BAYER AG (DE) | 1979-11-14 | — | — | EP | disclosed |
| US-4039334-A | ORGANIC SILVER SALT AND HALIDE, REDUCING AGENT, ROSIN | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-02 | — | — | US | disclosed |
| US-4036647-A | Package for making photopolymerized plates | HUGHES AIRCRAFT COMPANY (US) | 1977-07-19 | — | — | US | disclosed |
| US-4001017-A | REDOX CATALYSTS, DIAZINES, ELECTRON DONORS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964942-B2 | SSAO inhibitors and use thereof | SSB, HAO1, SORD | CYP2A6 727/4885CES2 2590/4885CES1 838/4885 |
| US-20250326721-A1 | SSAO INHIBITORS AND USE THEREOF | SSB, HAO1, SORD | CYP2A6 727/4885CES2 2590/4885CES1 838/4885 |
| US-20240190821-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF | PACSIN2, TPX2, PRSS12 | CYP2A6 3022/4885CES2 2317/4885CES1 2212/4885 |
| US-11744896-B2 | Compositions, use, and method for CDK2-PROTACs for cancer therapy and hearing loss | CDK2, CDK20, CDK2AP2 | CYP2A6 3992/4885CES2 4793/4885CES1 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.