Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728325 | 0.91 | TAAR1 (0.33) | TAAR1ALDH1A1POLBMAPT | |
| SCHEMBL6655889 | 0.84 | TAAR1 (0.33) | TAAR1 | |
| SCHEMBL6652403 | 0.84 | ALDH1A1 (0.33) | TAAR1ALDH1A1POLBMAPT | |
| SCHEMBL729843 | 0.84 | TAAR1 (0.30) | TAAR1 | |
| SCHEMBL13027724 | 0.80 | TAAR1 (0.32) | TAAR1ALDH1A1POLBMAPT | |
| SCHEMBL2338377 | 0.80 | CYP4F2 (0.32) | — | |
| SCHEMBL13027769 | 0.76 | ALDH1A1 (0.32) | TAAR1ALDH1A1POLBMAPT | |
| SCHEMBL5493495 | 0.75 | SMN1; SMN2 (0.41) | TAAR1ALDH1A1MAPT | |
| SCHEMBL13027883 | 0.75 | CYP1A2 (0.34) | ALDH1A1POLBMAPT | |
| SCHEMBL729902 | 0.74 | IDO1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218561-B1 | REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-04-17 | — | — | US | claimed |
| US-5684171-A | FROM DITHIODIMORPHOLINE AND A MERCAPTOSILANE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-11-04 | — | — | US | claimed |
| US-5675014-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-10-07 | — | — | US | claimed |
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | claimed |
| EP-0785207-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0718302-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-06-26 | — | — | EP | claimed |
| US-5440064-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-08-08 | — | — | US | claimed |
| EP-1178077-B1 | The preparation of surface modified silica | GOODYEAR TIRE & RUBBER (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6727374-B2 | TRIALKOXYSILYLHYDROCARBYL CYCLOHEXYL DISULFIDE, MADE BY REACTING N-CYCLOHEXYLTHIOPHTHALIMIDE AND A MERCAPTOALKOXYSILANE; SULFUR VULCANIZED RUBBER TIRES, BELTS AND HOSES | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-27 | — | — | US | disclosed |
| US-6593433-B2 | Alkoxysilylalkylammonium salts of alkoxysilylalkyl mercaptans used for processing sulfur-vuncanizable rubber compositions containing fillers | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-07-15 | — | — | US | disclosed |
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | disclosed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | disclosed |
| EP-1178077-A1 | The preparation of surface modified silica | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-0794221-A1 | Process for the preparation of a particulate reinforced rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0785207-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0718302-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5440064-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022085-A1 | Preparation of surface modified silica | OSTC, SAMM50, SSRP1 | TAAR1 1485/4885ALDH1A1 3796/4885POLB 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.