Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728326 | 0.98 | HDAC3 (0.38) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6655894 | 0.85 | HDAC3 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9001096 | 0.83 | TSHR (0.40) | HDAC6 | |
| SCHEMBL109759 | 0.82 | TSHR (0.38) | — | |
| SCHEMBL730157 | 0.80 | HDAC3 (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2338379 | 0.80 | HDAC3 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5549263 | 0.79 | LTA4H (0.39) | — | |
| SCHEMBL729853 | 0.78 | HDAC3 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28458022 | 0.76 | TAAR1 (0.41) | — | |
| SCHEMBL106489 | 0.76 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218561-B1 | REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-04-17 | — | — | US | claimed |
| US-5684171-A | FROM DITHIODIMORPHOLINE AND A MERCAPTOSILANE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-11-04 | — | — | US | claimed |
| US-5675014-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-10-07 | — | — | US | claimed |
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | claimed |
| EP-0785207-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0718302-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-06-26 | — | — | EP | claimed |
| US-5440064-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-08-08 | — | — | US | claimed |
| EP-1178077-B1 | The preparation of surface modified silica | GOODYEAR TIRE & RUBBER (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6727374-B2 | TRIALKOXYSILYLHYDROCARBYL CYCLOHEXYL DISULFIDE, MADE BY REACTING N-CYCLOHEXYLTHIOPHTHALIMIDE AND A MERCAPTOALKOXYSILANE; SULFUR VULCANIZED RUBBER TIRES, BELTS AND HOSES | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-27 | — | — | US | disclosed |
| US-6593433-B2 | Alkoxysilylalkylammonium salts of alkoxysilylalkyl mercaptans used for processing sulfur-vuncanizable rubber compositions containing fillers | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-07-15 | — | — | US | disclosed |
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | disclosed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | disclosed |
| EP-1178077-A1 | The preparation of surface modified silica | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-0794221-A1 | Process for the preparation of a particulate reinforced rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0785207-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0718302-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5440064-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022085-A1 | Preparation of surface modified silica | OSTC, SAMM50, SSRP1 | HDAC3 2875/4885HDAC4 1403/4885HDAC1 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.