SCHEMBL728326

SCHEMBL728326

CCO[Si](OCC)(OCCCCS)c1ccccc1C

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6653016 0.98 HDAC3 (0.40) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL6655894 0.86 HDAC3 (0.39) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL109759 0.83 TSHR (0.38)
SCHEMBL730157 0.81 HDAC3 (0.33) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9001096 0.81 TSHR (0.40) HDAC6
SCHEMBL5549263 0.80 LTA4H (0.39)
SCHEMBL729853 0.80 HDAC3 (0.44) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2338379 0.78 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28458022 0.77 TAAR1 (0.41)
SCHEMBL106489 0.77 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710718-B Stabilized silane-modified polymer compositions and methods 迈图高新材料公司 2024-06-25 CN claimed
EP-3476876-B1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MAT INC (US) 2023-08-09 EP claimed
EP-3956376-A1 STABLE SILANE MODIFIED POLYMER COMPOSITION AND METHOD Momentive Performance Materials Inc. (US) 2022-02-23 EP claimed
CN-113710718-A Stable silane-modified polymer compositions and methods 迈图高新材料公司 2021-11-26 CN claimed
CN-108137772-B Process for preparing silylated polymers with low color and color stability 莫门蒂夫性能材料股份有限公司 2021-06-29 CN claimed
CN-108012542-B Process for preparing silylated polymers using a back-mixing step 莫门蒂夫性能材料股份有限公司 2021-02-19 CN claimed
US-20200332052-A1 STABILE SILANE MODIFIED POLYMER COMPOSITION AND METHOD MOMENTIVE PERFORMANCE MATERIALS INC. 2020-10-22 US claimed
WO-2020214935-A1 STABILE SILANE MODIFIED POLYMER COMPOSITION AND METHOD MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-10-22 WO claimed
EP-1874840-B1 SILYLATED POLYMER DERIVED FROM BUTADIENE AND SOLVENT-RESISTANT PRESSURE SENSITIVE ADHESIVE COMPOSITION CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2020-06-03 EP claimed
EP-3476876-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS Momentive Performance Materials Inc. (US) 2019-05-01 EP claimed
WO-2006118766-A1 SILYLATED POLYMER DERIVED FROM BUTADIENE AND SOLVENT-RESISTANT PRESSURE SENSITIVE ADHESIVE COMPOSITION CONTAINING SAME GENERAL ELECTRIC COMPANY (US) 2006-11-09 WO claimed
US-20060247370-A1 Silylated polymer derived from butadiene and solvent-resistant pressure sensitive adhesive composition containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2006-11-02 US claimed
US-6218561-B1 REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. THE GOODYEAR TIRE & RUBBER COMPANY 2001-04-17 US claimed
US-5684171-A FROM DITHIODIMORPHOLINE AND A MERCAPTOSILANE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-11-04 US claimed
US-5675014-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-10-07 US claimed
US-5663358-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-02 US claimed
EP-0785207-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP claimed
EP-0785206-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-07-23 EP claimed
EP-0718302-A1 Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-06-26 EP claimed
US-5440064-A Process for the preparation of organosilicon disulfide compounds THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-08-08 US claimed