Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591038 | 0.84 | KCNMA1 (0.65) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL30388557 | 0.83 | KCNMA1 (0.63) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL5144247 | 0.83 | KCNMA1 (0.63) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL12832472 | 0.82 | ATM (0.60) | L3MBTL1SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL5528035 | 0.81 | KCNMA1 (0.62) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL7321997 | 0.78 | KCNMA1 (0.58) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL11227724 | 0.78 | KCNMA1 (0.58) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL18725484 | 0.78 | TSHR (0.55) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL9539950 | 0.77 | KCNMA1 (0.57) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL27599949 | 0.77 | KCNMA1 (0.56) | KCNMA1TDP1L3MBTL1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1298706-C | Insecticidal diamides | DU PONT (US) | 2007-02-07 | — | — | CN | disclosed |
| CN-1555364-A | Insecticidal diamides | �Ű˾ | 2004-12-15 | — | — | CN | disclosed |
| US-20040235959-A1 | Insecticidal diamides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-11-25 | — | — | US | disclosed |
| EP-1427705-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003026415-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | DDT, NRDC, NOXO1 | KCNMA1 1240/4885TDP1 2624/4885L3MBTL1 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.