Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322003 | 0.85 | ALDH1A1 (0.54) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL11591038 | 0.83 | KCNMA1 (0.65) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL5144247 | 0.81 | KCNMA1 (0.63) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL30388557 | 0.81 | KCNMA1 (0.63) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL11497425 | 0.81 | NLRP3 (0.57) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL5528035 | 0.80 | KCNMA1 (0.62) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL11227724 | 0.79 | KCNMA1 (0.58) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL6653285 | 0.78 | KCNMA1 (0.59) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL14068450 | 0.77 | SMN1; SMN2 (0.51) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR | |
| SCHEMBL1148045 | 0.76 | KCNMA1 (0.54) | KCNMA1L3MBTL1TDP1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |