Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 4/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650193 | 0.83 | DAO (0.43) | PDE3BPDE3ADAO | |
| SCHEMBL6648289 | 0.83 | MAOB (0.43) | PDE3BPDE3ADAO | |
| SCHEMBL6647299 | 0.74 | DAO (0.52) | PDE3BPDE3ADAO | |
| SCHEMBL5215190 | 0.70 | DAO (0.49) | PDE3BPDE3ADAOMEN1KMT2A | |
| SCHEMBL6652310 | 0.68 | MAPK14 (0.47) | PDE3BPDE3ADAOKMT2AL3MBTL1 | |
| SCHEMBL6648037 | 0.68 | THRA (0.41) | PDE3BPDE3ADAO | |
| SCHEMBL6471595 | 0.67 | DAO (0.39) | PDE3BPDE3ADAO | |
| SCHEMBL4466645 | 0.67 | MAPK14 (0.51) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL6652379 | 0.66 | KMT2A (0.41) | PDE3BPDE3ADAOKMT2A | |
| SCHEMBL13119197 | 0.66 | TAAR1 (0.53) | ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | Pharmacia Corporation (US) | 2004-12-29 | — | — | EP | claimed |
| WO-2003068230-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORPORATION (US) | 2003-08-21 | — | — | WO | claimed |
| EP-1490064-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | Pharmacia Corporation (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003068230-A1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORPORATION (US) | 2003-08-21 | — | — | WO | disclosed |