Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481334 | 1.00 | TP53 (0.47) | TP53P2RX7RAB9ACYP2C9CYP2C19 | |
| SCHEMBL6653340 | 1.00 | TP53 (0.47) | TP53P2RX7RAB9ACYP2C9CYP2C19 | |
| SCHEMBL9873547 | 0.83 | ALDH1A1 (0.45) | GAAALDH1A1HPGD | |
| SCHEMBL9873550 | 0.83 | ALDH1A1 (0.45) | GAAALDH1A1HPGD | |
| SCHEMBL13145215 | 0.82 | TP53 (0.52) | TP53RAB9AKMT2APOLBGAA | |
| SCHEMBL4480840 | 0.76 | TP53 (0.60) | TP53RAB9ACYP2C9CYP2C19HTR2B | |
| SCHEMBL4480837 | 0.76 | TP53 (0.60) | TP53RAB9ACYP2C9CYP2C19HTR2B | |
| SCHEMBL1308046 | 0.74 | RAB9A (0.58) | TP53RAB9ACYP2C9CYP2C19HTR2B | |
| SCHEMBL3456288 | 0.74 | HPGD (0.63) | TP53RAB9AKMT2APOLBGAA | |
| SCHEMBL23533047 | 0.73 | DPP4 (0.40) | RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399450-A1 | BENZOXAZEPINE DERIVATIVES AND THEIR USE AS AMPA RECEPTOR STIMULATORS | Akzo Nobel N.V. (NL) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100865-A1 | BENZOXAZEPINE DERIVATIVES AND THEIR USE AS AMPA RECEPTOR STIMULATORS | AKZO NOBEL N.V. (NL) | 2002-12-19 | — | — | WO | disclosed |