Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873550 | 1.00 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1CASRPIK3CDACHE | |
| SCHEMBL9874281 | 0.83 | PREP (0.59) | ALDH1A1GAA | |
| SCHEMBL9874283 | 0.83 | PREP (0.59) | ALDH1A1GAA | |
| SCHEMBL6653335 | 0.83 | TP53 (0.47) | ALDH1A1GAAHPGD | |
| SCHEMBL6653340 | 0.83 | TP53 (0.47) | ALDH1A1GAAHPGD | |
| SCHEMBL4481334 | 0.83 | TP53 (0.47) | ALDH1A1GAAHPGD | |
| SCHEMBL15723639 | 0.82 | PIK3CD (0.58) | ALDH1A1L3MBTL1PIK3CDACHEGAA | |
| SCHEMBL9873989 | 0.82 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1SLC6A1 | |
| SCHEMBL9872319 | 0.81 | SLC6A1 (0.54) | ALDH1A1L3MBTL1PIK3CDACHEGAA | |
| SCHEMBL9872312 | 0.81 | SLC6A1 (0.54) | ALDH1A1L3MBTL1PIK3CDACHEGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |