Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479241 | 0.80 | LMNA (0.41) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL20156793 | 0.80 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL56243 | 0.79 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL29717597 | 0.79 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL28477211 | 0.78 | ALDH1A1 (0.46) | CYP3A4LMNAHPGDTSHRBLM | |
| SCHEMBL104314 | 0.78 | GABRA1 (0.55) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL16955337 | 0.78 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL9619802 | 0.78 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL850254 | 0.78 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2CYP1A2 | |
| SCHEMBL22195421 | 0.77 | HTR2A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248521-B | K-RAS G12C inhibitor and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-113248521-A | K-RAS G12C inhibitor and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2021-08-13 | — | — | CN | disclosed |
| EP-2008336-B1 | LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-09-12 | — | — | EP | disclosed |
| US-7642324-B2 | Methods of using heterocycle-amine ligands, compositions, complexes, and catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-20090131619-A1 | METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS | SYMYX TECHNOLOGIES, INC. (US) | 2009-05-21 | — | — | US | disclosed |
| US-20040144655-A1 | Process for depositing strong adherend polymer coating onto an electrically conductive surface | UNIVERSITE DE LIEGE (BE) | 2004-07-29 | — | — | US | disclosed |
| EP-1425315-A2 | PROCESS FOR DEPOSITING STRONG ADHEREND POLYMER COATING ONTO AN ELECTRICALLY CONDUCTIVE SURFACE | University of Liege (BE) | 2004-06-09 | — | — | EP | disclosed |
| WO-2002098926-A2 | PROCESS FOR DEPOSITING STRONG ADHEREND POLYMER COATING ONTO AN ELECTRICALLY CONDUCTIVE SURFACE | UNIVERSITE DE LIEGE (BE) | 2002-12-12 | — | — | WO | disclosed |
| US-4208491-A | AT RANDOHLY DISTRIBUTED CONJUGATED UNSATURATION SITES | EXXON RESEARCH & ENGINEERING CO. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4160758-A | COMBINING PASTE OF UNSATURATED POLYESTER, FREE RADICAL POLYMERIZABLE MONOMER AND INORGANIC FILLER WITH PASTE OF CONJUGATED DIENE BUTYL ELASTOMER COPOLYMER | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4160759-A | UNSATURATED POLYESTER, CONJUGATED DIENE BUTYL ELASTOMER | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-07-10 | — | — | US | disclosed |