SCHEMBL6653471

SCHEMBL6653471

C=CC(=O)O[Si](CCC)(OC)OC

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.41
HPGD P15428 1/20 0.41
THRB P10828 3/20 0.35
ALDH1A1 P00352 4/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.32
ZDHHC2 Q9UIJ5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28398210 0.90 THRB (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL1012383 0.89 TSHR (0.47) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL4392894 0.87 HPGD (0.35) TSHRHPGDTHRB
Acrylic Acid Methyl Ester SCHEMBL27688298 0.85 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL947094 0.84 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL29053271 0.83 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
Acrylic Acid SCHEMBL15876790 0.80 LMNA (0.42) TSHRHPGDTHRBALDH1A1HSD17B10
SCHEMBL2961784 0.79 ATM (0.31)
SCHEMBL4395295 0.79 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL545230 0.79 TSHR (0.44) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP claimed
US-20240399627-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-12-05 US claimed
WO-2024246819-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-12-05 WO claimed
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
CN-120129988-A Photocurable composition for sealing material of lithium ion secondary battery 东亚合成株式会社 2025-06-10 CN disclosed
WO-2024246819-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-12-05 WO disclosed
US-20240399627-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-12-05 US disclosed
US-12152142-B2 Shoe-sole rubber composition and shoe ASICS CORPORATION (JP) 2024-11-26 US disclosed
CN-113195547-B Photocurable composition for imprinting 日产化学株式会社 2023-08-11 CN disclosed
CN-108333869-B Photosensitive composition, cured film, method for producing same, and display element, light-emitting element, and light-receiving element JSR株式会社 2023-07-18 CN disclosed
EP-1431356-B1 Use of aqueous dipersion of particles made up of polymerisate and fine inorganic solid material for priming mineral substrates BASF SE (DE) 2015-05-13 EP disclosed
EP-1431356-A2 Use of aqueous dipersion of particles made up of polymerisate and fine inorganic solid material for priming mineral substrates Basf AG (DE) 2004-06-23 EP disclosed
CN-1140575-C Vinyl chloride resin composition ��Ԩ��ѧ��ҵ��ʽ���� 2004-03-03 CN disclosed
CN-1366540-A Vinyl chloride resin composition KANEKA CORP (JP) 2002-08-28 CN disclosed
CN-1085997-C Polycarbonate resin composition GEN ELECTRIC (US) 2002-06-05 CN disclosed
CN-1344290-A Polycarbonate resin compsn. GEN ELECTRIC (US) 2002-04-10 CN disclosed
CN-1061067-C Impact resistant resin composition GEN ELECTRIC (US) 2001-01-24 CN disclosed
CN-1135230-A Polycarbonate resin composition GEN ELECTRIC (US) 1996-11-06 CN disclosed
CN-1110695-A Impact resistant resin composition GEN ELECTRIC (US) 1995-10-25 CN disclosed
EP-0097516-B1 FILLER-CONTAINING POLYMER PARTICLES USEFUL AS CARRIERS FOR SUPPORTING A BIOLOGICAL SUBSTANCE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-08-23 EP disclosed