Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 6/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.46 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.46 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.46 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.46 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.46 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653539 | 1.00 | MTNR1A (0.54) | MTNR1APTGESALOX15HDAC3HDAC4 | |
| SCHEMBL6651695 | 0.86 | ALOX15 (0.55) | MTNR1APTGESALOX15HDAC3HDAC4 | |
| SCHEMBL6651692 | 0.86 | ALOX15 (0.55) | MTNR1APTGESALOX15HDAC3HDAC4 | |
| SCHEMBL31438947 | 0.85 | ICMT (0.56) | MTNR1APTGESALOX15TRPV1 | |
| SCHEMBL7033631 | 0.85 | ICMT (0.56) | MTNR1APTGESALOX15TRPV1 | |
| SCHEMBL6652681 | 0.85 | ICMT (0.56) | MTNR1APTGESALOX15TRPV1 | |
| SCHEMBL31438944 | 0.85 | ICMT (0.56) | MTNR1APTGESALOX15TRPV1 | |
| SCHEMBL6653805 | 0.85 | ICMT (0.56) | MTNR1APTGESALOX15TRPV1 | |
| SCHEMBL6650885 | 0.84 | MTNR1A (0.58) | MTNR1APTGESALOX15HDAC3HDAC4 | |
| SCHEMBL6650890 | 0.84 | MTNR1A (0.58) | MTNR1APTGESALOX15HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875501-B1 | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| EP-0802196-B1 | Alkylenediamine derivatives as drugs for the treatment of ulcers and the inhibition of Helicobacter pylori | SHISEIDO CO LTD (JP) | 2001-08-29 | — | — | EP | disclosed |
| US-6043243-A | Pyrrolidine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |
| US-6001880-A | DISUBSTITUTED N-(2-DIALKYLAMINOETHYL)BENZAMIDE DERIVATIVES OF GIVEN FORMULA; ANTIBACTERIAL ACTIVITY AGAINST HELICOBACTER PYROLI, ADMINISTERING FOR THE PREVENTION OR CURE OF PEPTIC ULCERS | SHISEIDO CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5925667-A | INHIBITS GROWTH OF HELICOBACTER PYLORI | SHISEIDO CO., LTD. (JP) | 1999-07-20 | — | — | US | disclosed |
| EP-0875501-A2 | Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0869118-A1 | Pyrrolidine derivative, anti-ulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1998-10-07 | — | — | EP | disclosed |
| US-5814634-A | PEPTIC ULCERS, GASTRIC ULCERS | SHISEIDO CO. LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0802196-A1 | Alkylenediamine derivative, antiulcer drug, and antibacterial drug | SHISEIDO COMPANY LIMITED (JP) | 1997-10-22 | — | — | EP | disclosed |