Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164540 | 0.83 | CHIA (0.56) | CHIAP2RX7LMNAL3MBTL1KDM4E | |
| SCHEMBL5418289 | 0.83 | P2RX7 (0.70) | CHIAP2RX7LMNAL3MBTL1KDM4E | |
| SCHEMBL14284671 | 0.82 | P2RX7 (0.44) | CHIAP2RX7LMNAKDM4EHPGD | |
| SCHEMBL4600712 | 0.82 | NAAA (0.65) | LMNAL3MBTL1KDM4EHTTHPGD | |
| SCHEMBL13687262 | 0.81 | NAPRT (0.56) | CHIAP2RX7LMNAL3MBTL1KDM4E | |
| SCHEMBL30267808 | 0.81 | CHIA (0.55) | CHIAP2RX7LMNAL3MBTL1KDM4E | |
| SCHEMBL29520153 | 0.81 | PRKCI (0.58) | CHIAP2RX7L3MBTL1KDM4EHPGD | |
| SCHEMBL13973141 | 0.81 | PRKCI (0.58) | CHIAP2RX7L3MBTL1KDM4EHPGD | |
| SCHEMBL13702282 | 0.81 | SMN1; SMN2 (0.59) | CHIALMNAHTTHPGDKMT2A | |
| SCHEMBL27923137 | 0.81 | CHIA (0.55) | CHIAP2RX7LMNAL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080081-B1 | BENZOFUROXAN DERIVATIVES AND THEIR USE IN TREATING ANGINA PECTORIS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-06-30 | — | — | EP | disclosed |
| US-6248895-B1 | USED FOR CARDIOVASCULAR DISORDERS | TORRENT PHARMACEUTICALS LTD. (IN) | 2001-06-19 | — | — | US | disclosed |