Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | GUSB | P08236 | 3/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027631 | 0.81 | TNKS (0.54) | NPC1RAB9AKDM4EALDH1A1TP53 | |
| SCHEMBL17251750 | 0.78 | MAPT (0.50) | NPC1RAB9AKDM4EALDH1A1TP53 | |
| SCHEMBL10566368 | 0.76 | TNKS (0.58) | NPC1RAB9AKDM4EALDH1A1TP53 | |
| SCHEMBL6653651 | 0.76 | TNKS (0.51) | NPC1RAB9AKDM4EALDH1A1TP53 | |
| SCHEMBL6654779 | 0.76 | PDE3B (0.50) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL12696294 | 0.73 | TNKS (0.52) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6656241 | 0.72 | PDE3B (0.50) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2267250 | 0.72 | NPC1 (0.66) | NPC1RAB9AKDM4EALDH1A1TP53 | |
| SCHEMBL7553361 | 0.71 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1TP53 | |
| SCHEMBL6373232 | 0.71 | NPC1 (0.49) | NPC1RAB9AKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |