Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | GUSB | P08236 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12696294 | 0.90 | TNKS (0.52) | TNKSTNKS2PARP2NPC1RAB9A | |
| SCHEMBL7553361 | 0.87 | NPC1 (0.53) | TNKSTNKS2PARP2NPC1RAB9A | |
| SCHEMBL6528644 | 0.84 | KDM4E (0.56) | TNKSNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6653652 | 0.81 | NPC1 (0.51) | TNKSTNKS2PARP2NPC1RAB9A | |
| SCHEMBL28160736 | 0.81 | PDE5A (0.46) | TNKSTNKS2NPC1RAB9AKDM4E | |
| SCHEMBL17251750 | 0.81 | MAPT (0.50) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9045175 | 0.79 | ALDH1A1 (0.55) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15775406 | 0.79 | TNKS (0.63) | TNKSTNKS2PARP2NPC1RAB9A | |
| SCHEMBL10566368 | 0.79 | TNKS (0.58) | TNKSTNKS2PARP2NPC1RAB9A | |
| SCHEMBL5202015 | 0.78 | RPS6KA2 (0.45) | NPC1RAB9APKMNQO2GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103755642-B | The synthetic method of 2-aryl benzoglyoxaline | CHENGDU UNIVERSITY OF TECHNOLOGY (CN) | 2015-09-30 | — | — | CN | disclosed |