Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656241 | 0.78 | PDE3B (0.50) | PDE3BPDE3ANQO2CYP19A1AMY1A | |
| SCHEMBL7483023 | 0.77 | MEN1 (0.53) | PDE3BPDE3AAMY1ATYMSKDM4E | |
| SCHEMBL24821720 | 0.77 | MAPT (0.38) | PDE3BPDE3ATERTTYMSKDM4E | |
| SCHEMBL4611131 | 0.76 | ALDH1A1 (0.46) | PDE3BPDE3ANQO2AMY1AKDM4E | |
| SCHEMBL13383928 | 0.76 | ALDH1A1 (0.48) | TYMSKDM4EHSD17B10LMNAALDH1A1 | |
| SCHEMBL6653652 | 0.76 | NPC1 (0.51) | PDE3BPDE3AAMY1AKDM4EHSD17B10 | |
| SCHEMBL6654449 | 0.73 | PDE3B (0.43) | PDE3BPDE3ATERTAMY1AMAPK1 | |
| SCHEMBL2272231 | 0.72 | PDE4A (0.49) | PDE3BPDE3ANQO2CYP19A1TYMS | |
| SCHEMBL6654775 | 0.71 | PDE3B (0.43) | PDE3BPDE3ANQO2CYP19A1TERT | |
| SCHEMBL620475 | 0.71 | NQO2 (0.51) | PDE3BPDE3ANQO2CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |