Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654658 | 1.00 | EGFR (0.55) | EGFRPLA2G2DZDHHC2HDAC8HTT | |
| SCHEMBL6659156 | 0.80 | EGFR (0.56) | EGFRZDHHC2HTTPTGS2PTGS1 | |
| SCHEMBL6659147 | 0.80 | EGFR (0.56) | EGFRZDHHC2HTTPTGS2PTGS1 | |
| SCHEMBL4839224 | 0.80 | ALDH1A1 (0.61) | PLA2G2DHDAC8MEN1ALDH1A1KMT2A | |
| SCHEMBL4839242 | 0.80 | ALDH1A1 (0.61) | PLA2G2DHDAC8MEN1ALDH1A1KMT2A | |
| SCHEMBL5524486 | 0.79 | HDAC8 (0.58) | PLA2G2DHDAC8MEN1ALDH1A1KMT2A | |
| SCHEMBL5524484 | 0.79 | HDAC8 (0.58) | PLA2G2DHDAC8MEN1ALDH1A1KMT2A | |
| SCHEMBL23344644 | 0.78 | APP (0.55) | EGFRZDHHC2HDAC8PTGS2PTGS1 | |
| SCHEMBL1549366 | 0.78 | MEN1 (0.56) | PLA2G2DHDAC8L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL1549368 | 0.78 | MEN1 (0.56) | PLA2G2DHDAC8L3MBTL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040254241-A1 | Enzyme inhibitor; cognition activators | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-12-16 | — | — | US | disclosed |
| EP-1431280-A1 | ARYL SULFAMATE DERIVATIVES | Kyowa Hakko Kogyo Co., Ltd (JP) | 2004-06-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254241-A1 | Enzyme inhibitor; cognition activators | SULT1A1, STS, CYP26A1 | EGFR 2088/4885PLA2G2D 4129/4885ZDHHC2 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.