Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286019 | 0.81 | TSHR (0.43) | PDE3BPDE3AAMY1AALDH1A1TSHR | |
| SCHEMBL7483015 | 0.78 | MEN1 (0.54) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6656239 | 0.78 | CACNA1H (0.45) | PDE3BPDE3AAMY1ACYP1A2KDM4E | |
| SCHEMBL4611125 | 0.76 | ALDH1A1 (0.55) | PDE3BPDE3AALDH1A1HPGDHSD17B10 | |
| SCHEMBL13594653 | 0.76 | ADRB2 (0.52) | CYP1A2KDM4EALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL6653651 | 0.76 | TNKS (0.51) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL1080091 | 0.74 | PARP1 (0.42) | KDM4EALDH1A1MEN1LMNATSHR | |
| SCHEMBL13255445 | 0.74 | PARP1 (0.46) | KDM4EALDH1A1HPGDADRB2PARP1 | |
| SCHEMBL6654447 | 0.73 | CACNA1H (0.42) | PDE3BPDE3ATERTCYP1A2KDM4E | |
| SCHEMBL20100921 | 0.72 | BRD4 (0.61) | KDM4EALDH1A1HSD17B10TP53PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |