SCHEMBL6654910

SCHEMBL6654910

N#Cc1cc(Cl)c([NH])c(Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 3/20 0.39
TTR P02766 2/20 0.36
ALB P02768 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GPR35 Q9HC97 1/20 0.34
AR P10275 2/20 0.34
GRM5 P41594 3/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
TRPV4 Q9HBA0 1/20 0.32
TSHR P16473 1/20 0.32
FASN P49327 1/20 0.31
RHEB Q15382 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7931074 0.78 VCAM1 (0.46) VCAM1TTRALBMEN1KMT2A
SCHEMBL15850516 0.76 VCAM1 (0.40) VCAM1TTRALBMEN1KMT2A
SCHEMBL22664414 0.76 TTR (0.48) VCAM1TTRALBMEN1KMT2A
SCHEMBL1752587 0.74 ALDH1A1 (0.50) VCAM1TTRALBMEN1KMT2A
SCHEMBL136860 0.74 TTR (0.52) VCAM1TTRALBMEN1KMT2A
SCHEMBL9088175 0.74 VCAM1 (0.43) VCAM1TTRALBMEN1KMT2A
SCHEMBL4897669 0.74 TTR (0.52) VCAM1TTRALBMEN1KMT2A
Water SCHEMBL10768309 0.74 TTR (0.52) VCAM1TTRALBMEN1KMT2A
SCHEMBL7929409 0.74 GRM5 (0.46) VCAM1TTRALBMEN1KMT2A
SCHEMBL9515292 0.74 TTR (0.46) VCAM1TTRALBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833203-B1 Anthraquinone compounds NIPPON CATALYTIC CHEM IND (JP) 2004-06-16 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed