SCHEMBL7931074

SCHEMBL7931074

N#Cc1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 3/20 0.46
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 3/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 2/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
GPR35 Q9HC97 1/20 0.41
TTR P02766 2/20 0.39
ALB P02768 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
AR P10275 2/20 0.36
AHR P35869 4/20 0.36
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4386055 0.85 VCAM1 (0.41) VCAM1ALDH1A1CYP3A4GPR35TTR
SCHEMBL9710858 0.83 VCAM1 (0.39) VCAM1ALDH1A1GPR35TTRALB
SCHEMBL22664414 0.80 TTR (0.48) VCAM1GPR35TTRALBMEN1
SCHEMBL15850516 0.80 VCAM1 (0.40) VCAM1ALDH1A1CYP3A4HPGDGPR35
SCHEMBL4897669 0.78 TTR (0.52) VCAM1ALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL136860 0.78 TTR (0.52) VCAM1ALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL6654910 0.78 VCAM1 (0.39) VCAM1GPR35TTRALBMEN1
Water SCHEMBL10768309 0.78 TTR (0.52) VCAM1ALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL1752587 0.78 ALDH1A1 (0.50) VCAM1ALDH1A1CYP3A4GPR35TTR
SCHEMBL9088175 0.78 VCAM1 (0.43) VCAM1GPR35TTRALBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0441004-B1 Process for preparing aromatic nitriles ENICHEM SINTESI (IT) 1995-09-06 EP claimed
EP-0441004-A1 Process for preparing aromatic nitriles ENICHEM SYNTHESIS S.p.A. (IT) 1991-08-14 EP claimed
CN-121378048-A Preparation method of 3,4, 5-trichloronitrile 湖南化工研究院有限公司 2026-01-23 CN disclosed
EP-2887802-A2 METHODS OF SOIL PEST CONTROL Syngenta Participations AG (CH) 2015-07-01 EP disclosed
WO-2014029710-A2 METHODS OF SOIL PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029707-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
EP-1140735-A1 PREPARATION OF NUCLEAR CHLORINATED AROMATIC COMPOUNDS OCCIDENTAL CHEMICAL CORPORATION (US) 2001-10-10 EP disclosed
WO-2000040524-A1 PREPARATION OF NUCLEAR CHLORINATED AROMATIC COMPOUNDS OCCIDENTAL CHEMICAL CORPORATION (US) 2000-07-13 WO disclosed
US-5981789-A CHLORODENITRATING AROMATIC COMPOUNDS USING LESS CHLORINATING AGENT AND LOWER TEMPERATURES, THEN RECYCLING THE PRODUCT MIXTURE TO INCREASE THE YIELD OCCIDENTAL CHEMICAL CORPORATION (US) 1999-11-09 US disclosed
EP-0441004-B1 Process for preparing aromatic nitriles ENICHEM SINTESI (IT) 1995-09-06 EP disclosed
WO-1992018467-A1 CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1992-10-29 WO disclosed
US-5104878-A Insecticides, miticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-14 US disclosed
EP-0441004-A1 Process for preparing aromatic nitriles ENICHEM SYNTHESIS S.p.A. (IT) 1991-08-14 EP disclosed
EP-0396250-A1 Pyrimidinone derivatives ZENECA LIMITED (GB) 1990-11-07 EP disclosed
US-4704483-A FLUORINATION WITH POTASSIUM FLUORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1987-11-03 US disclosed
US-4582948-A VAPOR PHASE CHLORO-DENITRATION REACTION OCCIDENTAL CHEMICAL CORPORATION (US) 1986-04-15 US disclosed
EP-0159388-A2 Preparation of nuclear chlorinated compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1985-10-30 EP disclosed