⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27967901 | 0.78 | ALDH1A1 (0.48) | — | |
| SCHEMBL701768 | 0.78 | — | — | |
| SCHEMBL6824660 | 0.72 | — | — | |
| SCHEMBL6823719 | 0.72 | — | — | |
| SCHEMBL6823712 | 0.72 | — | — | |
| SCHEMBL10655372 | 0.71 | TRPM8 (0.52) | — | |
| SCHEMBL6356265 | 0.70 | GABBR2 (0.61) | — | |
| SCHEMBL15058409 | 0.70 | ALDH1A1 (0.42) | — | |
| SCHEMBL1890478 | 0.69 | — | — | |
| SCHEMBL13057236 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2884985-A1 | TOPICAL SKIN CARE COMPOSITION | Jafer Limited (VG) | 2015-06-24 | — | — | EP | claimed |
| US-20150125406-A1 | TOPICAL SKIN CARE COMPOSITION | JAFER LIMITED (VG) | 2015-05-07 | — | — | US | claimed |
| WO-2014028032-A1 | TOPICAL SKIN CARE COMPOSITION | JAFER LIMITED (VG) | 2014-02-20 | — | — | WO | claimed |
| EP-0897717-B1 | Whitening skin cosmetic composition and melanogenic inhibitor agent containing such cosmetic composition | EXSYMOL SA (MC) | 2004-06-09 | — | — | EP | claimed |
| US-6280715-B1 | APPLYING AMINOORGANOPHOSPHONIC ACID OR -PHOSPHINIC ACID DERIVATIVE AND ORGANOSILICON COMPOUND | EXSYMOL S.A.M. (MC) | 2001-08-28 | — | — | US | claimed |
| EP-2884985-A1 | TOPICAL SKIN CARE COMPOSITION | Jafer Limited (VG) | 2015-06-24 | — | — | EP | disclosed |
| US-20150125406-A1 | TOPICAL SKIN CARE COMPOSITION | JAFER LIMITED (VG) | 2015-05-07 | — | — | US | disclosed |
| WO-2014028032-A1 | TOPICAL SKIN CARE COMPOSITION | JAFER LIMITED (VG) | 2014-02-20 | — | — | WO | disclosed |
| US-6737416-B2 | THROMBOLYTIC AGENT HAVING HIGHER SAFETY | MEIJI SEIKA KAISHA LTD. (JP) | 2004-05-18 | — | — | US | disclosed |
| US-20030119787-A1 | Phosphonic acid derivative having inhibitory activity against carboxypeptidase B | MEIJI SEIKA KAISHA LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| US-6576627-B1 | Such as 7-amino-2-((2-methyl-1-(3-phenylpropanoylamino)-propyl)hydroxyphosphinoyl) -methylheptanoic acid; thrombotic disease | MEIJI SEIKA KAISHA LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| EP-1152004-B1 | Phosphonic acid derivatives having carboxypeptidase B inhibitory action | MEIJI SEIKA KAISHA (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1174434-A1 | Phosphonic acid derivative having inhibitory activity against carboxypeptidase B | MEIJI SEIKA KAISHA LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| EP-1152004-A1 | PHOSPHONIC ACID DERIVATIVES HAVING CARBOXYPEPTIDASE B INHIBITORY ACTIVITY | MEIJI SEIKA KAISHA LTD. (JP) | 2001-11-07 | — | — | EP | disclosed |
| US-6280715-B1 | APPLYING AMINOORGANOPHOSPHONIC ACID OR -PHOSPHINIC ACID DERIVATIVE AND ORGANOSILICON COMPOUND | EXSYMOL S.A.M. (MC) | 2001-08-28 | — | — | US | disclosed |