SCHEMBL6655029

SCHEMBL6655029

CCC([SiH3])C(=O)NC.CNC(C)=O.CNC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6342118 0.73 KDM4E (0.32)
SCHEMBL15159359 0.68 KDM4E (0.43) TSHRUSP2
SCHEMBL9715563 0.68
SCHEMBL9700755 0.68 ALDH1A1 (0.32)
SCHEMBL18510170 0.67
SCHEMBL4397 0.67
SCHEMBL20411614 0.67
SCHEMBL2401765 0.67 KDM4E (0.54) TSHR
SCHEMBL6871426 0.67
SCHEMBL13105113 0.67 MEN1 (0.41) TSHRUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1031611-B1 Room temperature fast curable silicone composition SHINETSU CHEMICAL CO (JP) 2004-07-21 EP disclosed
US-6306998-B1 POLYSILOXANES WITH BLOCKED HYDROXY GROUPS AND HYDROLYZABLE SILANE KETOXIME, ALKOXY, ACYLOXY, AMIDE AND AMINE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-10-23 US disclosed
EP-1031611-A1 Room temperature fast curable silicone composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-08-30 EP disclosed