SCHEMBL6655474

SCHEMBL6655474

CC1=NN(c2cc(S(=O)(=O)O)ccc2Cl)C(=O)/C1=C\c1ccc(N(C)C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.55
MEN1 O00255 8/20 0.55
ALDH1A1 P00352 7/20 0.52
HPGD P15428 2/20 0.52
HSD17B10 Q99714 1/20 0.52
MAPT P10636 8/20 0.47
L3MBTL1 Q9Y468 5/20 0.47
TDP1 Q9NUW8 3/20 0.47
ALPL P05186 1/20 0.47
ALPI P09923 1/20 0.47
ALPG P10696 1/20 0.47
KLKB1 P03952 1/20 0.44
CTSB P07858 1/20 0.44
GAA P10253 1/20 0.44
KAT8 Q9H7Z6 1/20 0.42
AMY1A P0DUB6 3/20 0.42
MAPK1 P28482 2/20 0.41
LMNA P02545 1/20 0.41
PKM P14618 1/20 0.41
OPRK1 P41145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6654968 1.00 KMT2A (0.55) KMT2AMEN1ALDH1A1HPGDHSD17B10
Ammonia Solution, Strong SCHEMBL6654696 0.99 KMT2A (0.54) KMT2AMEN1ALDH1A1HPGDHSD17B10
Ammonia Solution, Strong SCHEMBL6657933 0.99 KMT2A (0.54) KMT2AMEN1ALDH1A1HPGDHSD17B10
Ammonia Solution, Strong SCHEMBL6657936 0.99 KMT2A (0.54) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL29959849 0.94 KMT2A (0.50) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL14197588 0.88 MEN1 (0.54) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL6654602 0.83 ALDH1A1 (0.66) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL9875469 0.83 ALDH1A1 (0.66) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL11674150 0.83 ALDH1A1 (0.66) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL6654606 0.83 ALDH1A1 (0.66) KMT2AMEN1ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041953-B1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS WELLA AG (DE) 2004-07-07 EP claimed
US-20020010969-A1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2002-01-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010969-A1 AGENTS AND METHOD FOR PRODUCING TEMPORARY COLORATIONS OF KERATIN FIBERS KRT18, DSG1, SPTAN1 KMT2A 607/4885MEN1 2475/4885ALDH1A1 661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.