Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412917 | 0.89 | ALDH1A1 (0.35) | MAPTLMNAHTTALDH1A1MEN1 | |
| SCHEMBL5578465 | 0.76 | ALDH1A1 (0.36) | HTTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11825307 | 0.76 | NOTUM (0.43) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7958821 | 0.74 | CFTR (0.31) | MAPTLMNAHTTCFTRGOPC | |
| SCHEMBL27899163 | 0.73 | NOTUM (0.39) | MAPTLMNAHTTALDH1A1MEN1 | |
| SCHEMBL15511089 | 0.70 | ALDH1A1 (0.40) | LMNAHTTALDH1A1MEN1KMT2A | |
| SCHEMBL4633787 | 0.67 | MAPT (0.44) | MAPTLMNAHTTALDH1A1MEN1 | |
| SCHEMBL8656886 | 0.67 | MAPT (0.40) | MAPTLMNAHTTALDH1A1MEN1 | |
| SCHEMBL576916 | 0.66 | ALDH1A1 (0.47) | MAPTLMNAHTTALDH1A1MEN1 | |
| SCHEMBL6656042 | 0.65 | MAPT (0.42) | MAPTLMNAHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2956444-A1 | POSACONAZOLE IMMUNOASSAYS | ARK Diagnostics, Inc. (US) | 2015-12-23 | — | — | EP | disclosed |
| WO-2014126861-A1 | POSACONAZOLE IMMUNOASSAYS | ARK DIAGNOSTICS, INC. (US) | 2014-08-21 | — | — | WO | disclosed |
| US-8669371-B2 | Regioselective chlorination of the phenyl ring of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-ones | TAGROS CHEMICALS INDIA PVT LTD (IN) | 2014-03-11 | — | — | US | disclosed |
| US-20130072689-A1 | Regioselective chlorination of the phenyl ring of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-ones | TAGROS CHEMICALS INDIA, LTD. (IN) | 2013-03-21 | — | — | US | disclosed |
| US-5728834-A | Process for preparation of 4-aryl-1,2,4-triazol-3-ones | WYCKOFF CHEMICAL COMPANY, INC. (US) | 1998-03-17 | — | — | US | disclosed |