SCHEMBL4633787

SCHEMBL4633787

O=C1N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
LMNA P02545 3/20 0.43
HTT P42858 1/20 0.43
ALDH1A1 P00352 5/20 0.42
GAA P10253 3/20 0.40
IDO1 P14902 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
MAPK1 P28482 1/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CFTR P13569 1/20 0.39
GOPC Q9HD26 1/20 0.39
PLA2G10 O15496 1/20 0.39
BTK Q06187 1/20 0.38
NOTUM Q6P988 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8809436 0.85 MAPT (0.39) MAPTLMNAHTTALDH1A1GAA
SCHEMBL4669134 0.84 P2RX7 (0.38) MAPTLMNAHTTALDH1A1GAA
SCHEMBL8195881 0.84 ALDH1A1 (0.40) MAPTLMNAHTTALDH1A1GAA
SCHEMBL9755085 0.82 MAPT (0.45) MAPTLMNAHTTALDH1A1RAB9A
SCHEMBL12997586 0.77 ALDH1A1 (0.47) MAPTLMNAHTTALDH1A1IDO1
SCHEMBL237236 0.74 ALDH1A1 (0.44) MAPTLMNAHTTALDH1A1GAA
SCHEMBL8656886 0.72 MAPT (0.40) MAPTLMNAHTTALDH1A1GAA
SCHEMBL576916 0.71 ALDH1A1 (0.47) MAPTLMNAHTTALDH1A1IDO1
SCHEMBL10713188 0.70 ALDH1A1 (0.41) MAPTLMNAHTTALDH1A1GAA
SCHEMBL30816757 0.69 IDO1 (0.69) MAPTLMNAHTTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118065000-B Elastic cotton-like polyester fiber and preparation process thereof 江苏三联新材料股份有限公司 2024-10-29 CN claimed
CN-118065000-A Elastic cotton-like polyester fiber and preparation process thereof 江苏三联新材料股份有限公司 2024-05-24 CN claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
JP-9281731-A None JP disclosed
CN-118065000-B Elastic cotton-like polyester fiber and preparation process thereof 江苏三联新材料股份有限公司 2024-10-29 CN disclosed
CN-118065000-A Elastic cotton-like polyester fiber and preparation process thereof 江苏三联新材料股份有限公司 2024-05-24 CN disclosed
CN-105924644-B Polyarylsulfone and preparation method thereof 吉林省中科聚合工程塑料有限公司 2020-04-03 CN disclosed
EP-1928841-A1 AMINO-5- Ý4- (DIFLUOROMETHOXY) PHENYL¨-5-PHENYLIMIDAZOLONE COMPOUNDS AS INHIBITORS OF THE BETA-SECRETASE (BACE) Wyeth a Corporation of the State of Delaware (US) 2008-06-11 EP disclosed
EP-1162936-A4 BODY COATING COMPOSITION PYRAMID PRODUCTIONS INC (US) 2006-01-04 EP disclosed
EP-1095039-B1 NEW PHARMACEUTICALLY ACTIVE COMPOUNDS ASTRAZENECA AB (SE) 2003-08-27 EP disclosed
US-20030134886-A1 Pharmaceutically active compounds ASTRAZENECA AB, A SWEDISH CORPORATION 2003-07-17 US disclosed
US-4295850-A Commercial preparations of dry organic substances CIBA-GEIGY CORPORATION (US) 1981-10-20 US disclosed
US-4087240-A OPTICAL BRIGHTENER, HALOHYDROCARBON SOLVENT, 2-METHYL-2,4-PENTANEDIOL, AMMONIUM SALT OF CELLULOSE SULFATE CIBA-GEIGY CORPORATION (US) 1978-05-02 US disclosed
US-4031273-A POLYAMIDE FIBERS CIBA-GEIGY CORPORATION (US) 1977-06-21 US disclosed
US-3997343-A ZINC OXIDE GAF CORPORATION (US) 1976-12-14 US disclosed
US-3989860-A Repair technique for photoreceptors XEROX CORPORATION (US) 1976-11-02 US disclosed
US-3960755-A Detecting compositions and method of using same AMERICAN CYANAMID COMPANY (US) 1976-06-01 US disclosed
US-3955977-A GRAPHIC DISPLAYS XEROX CORPORATION (US) 1976-05-11 US disclosed
US-3948828-A COLORING POLYESTERS OR POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3931026-A ELECTRICALLY INSULATING ENCAPSULATING COMPOSITION FOR SEMICONDUCTOR DEVICES SEMIKRON GESELLSCHAFT FUR GLEICHRICHTERBAU UND ELEKTRONIK M.B.H. (DT) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030134886-A1 Pharmaceutically active compounds HTR3C, HTR6, CNR1 MAPT 4048/4885LMNA 1851/4885HTT 629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.