Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 15/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27281245 | 0.77 | TSHR (0.43) | TSHRFDPSLMNALAP3GGPS1 | |
| SCHEMBL6777911 | 0.71 | FDPS (0.44) | TSHRFDPSLMNALAP3 | |
| SCHEMBL7426381 | 0.67 | — | — | |
| Phosphoric Acid SCHEMBL8842719 | 0.66 | LAP3 (0.48) | TSHRFDPSLAP3CA12CA1 | |
| SCHEMBL760206 | 0.66 | — | — | |
| Phosphoric Acid SCHEMBL8842709 | 0.66 | LAP3 (0.48) | TSHRFDPSLAP3CA12CA1 | |
| SCHEMBL17072311 | 0.66 | — | — | |
| Phosphoric Acid SCHEMBL1360058 | 0.66 | LAP3 (0.48) | TSHRFDPSLAP3CA12CA1 | |
| SCHEMBL15349735 | 0.66 | — | — | |
| SCHEMBL8634496 | 0.64 | TSHR (0.61) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048316-A9 | POLYNUCLEOTIDES ENCODING NOVEL HUMAN MITOCHONDRIAL AND MICROSOMAL GLYCEROL-3-PHOSPHATE ACYL-TRANSFERASES AND VARIANTS THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2004-05-06 | — | — | WO | disclosed |
| WO-2003048316-A2 | POLYNUCLEOTIDES ENCODING NOVEL HUMAN MITOCHONDRIAL AND MICROSOMAL GLYCEROL-3-PHOSPHATE ACYL-TRANSFERASES AND VARIANTS THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | disclosed |