SCHEMBL6656072

SCHEMBL6656072

CCCNc1cc(Cl)c2c(c1O)CC(=O)N2

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CISD1 Q9NZ45 2/20 0.37
DRD2 P14416 3/20 0.36
DRD1 P21728 2/20 0.36
DRD4 P21917 2/20 0.36
DRD5 P21918 2/20 0.36
DRD3 P35462 2/20 0.36
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.33
CNR2 P34972 3/20 0.32
CNR1 P21554 1/20 0.32
AHR P35869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6662700 0.88 CISD1 (0.36) CISD1ALDH1A1SMN1; SMN2LMNACNR2
SCHEMBL6658731 0.84 DRD2 (0.35) DRD2DRD1DRD4DRD5DRD3
SCHEMBL6382632 0.80 CYP3A4 (0.38) ALDH1A1SMN1; SMN2LMNA
SCHEMBL6655341 0.80 LMNA (0.35) CISD1LMNACNR2CNR1
SCHEMBL6662193 0.75 DRD2 (0.47) DRD2DRD1DRD4DRD5DRD3
SCHEMBL6659302 0.75 CISD1 (0.36) CISD1ALDH1A1SMN1; SMN2LMNACNR2
SCHEMBL6658183 0.74 ADRB3 (0.35) ALDH1A1LMNA
SCHEMBL6381410 0.68 CYP3A4 (0.38) DRD2DRD1ALDH1A1SMN1; SMN2LMNA
SCHEMBL6659420 0.68 LMNA (0.34) ALDH1A1LMNA
SCHEMBL6382636 0.67 DRD2 (0.52) DRD2DRD1DRD4DRD5DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1438949-A1 Composition for dyeing keratinous fibres comprising an acylaminophenol coupler L'OREAL (FR) 2004-07-21 EP claimed
EP-1438949-A1 Composition for dyeing keratinous fibres comprising an acylaminophenol coupler L'OREAL (FR) 2004-07-21 EP disclosed