Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663836 | 0.92 | HDAC3 (0.32) | LMNACISD1 | |
| SCHEMBL6659420 | 0.83 | LMNA (0.34) | LMNA | |
| SCHEMBL6384831 | 0.82 | CYP3A4 (0.35) | LMNA | |
| SCHEMBL6659302 | 0.81 | CISD1 (0.36) | LMNACISD1PDE7BCNR1CNR2 | |
| SCHEMBL6383716 | 0.80 | ROCK2 (0.34) | LMNA | |
| SCHEMBL6656072 | 0.80 | CISD1 (0.37) | LMNACISD1CNR1CNR2 | |
| SCHEMBL6662700 | 0.79 | CISD1 (0.36) | LMNACISD1PDE7BCNR1CNR2 | |
| SCHEMBL6658396 | 0.79 | IDO1 (0.35) | LMNACNR1CNR2 | |
| SCHEMBL6662660 | 0.75 | BACE1 (0.35) | — | |
| SCHEMBL6384836 | 0.72 | DRD2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | claimed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |