Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654447 | 0.85 | CACNA1H (0.42) | CACNA1HPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL2431585 | 0.83 | TSHR (0.47) | PDE3BPDE3ADDAH1KDM4EALDH1A1 | |
| SCHEMBL6654775 | 0.78 | PDE3B (0.43) | CACNA1HPDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL2269491 | 0.75 | ADORA1 (0.50) | PDE3BPDE3ADDAH1KDM4EMEN1 | |
| SCHEMBL6656241 | 0.74 | PDE3B (0.50) | PDE3BPDE3ADDAH1KDM4EALDH1A1 | |
| SCHEMBL6653651 | 0.72 | TNKS (0.51) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL22533865 | 0.71 | DDAH1 (0.41) | PDE3BPDE3ADDAH1ADORA3ADORA2A | |
| SCHEMBL29424800 | 0.71 | DDAH1 (0.41) | PDE3BPDE3ADDAH1ADORA3ADORA2A | |
| SCHEMBL9847093 | 0.69 | CBFB (0.46) | DDAH1TP53ADORA3ADORA2AADORA1 | |
| SCHEMBL6657269 | 0.68 | DDAH1 (0.44) | DDAH1ADORA3ADORA2AADORA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |