Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656239 | 0.85 | CACNA1H (0.45) | CACNA1HKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6654449 | 0.77 | PDE3B (0.43) | KMT2ATERTPDE3BPDE3APARP1 | |
| Ammonia Solution, Strong SCHEMBL3664643 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1MAPTLMNAHPGD | |
| SCHEMBL6654775 | 0.73 | PDE3B (0.43) | CACNA1HKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6756137 | 0.73 | CBFB (0.42) | ALDH1A1KMT2AMAPTPARP1MAPK1 | |
| SCHEMBL6653125 | 0.72 | GPR84 (0.41) | ALDH1A1PARP1MAPK1 | |
| SCHEMBL2266470 | 0.72 | PDE10A (0.55) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL15767458 | 0.72 | SMN1; SMN2 (0.49) | CACNA1HKDM4EALDH1A1AAK1TP53 | |
| Ammonia Solution, Strong SCHEMBL3663348 | 0.71 | PDE10A (0.54) | KDM4EMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL6755252 | 0.70 | MGAM (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |