SCHEMBL255251

SCHEMBL255251

CC(C)CNC(=O)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.76
KMT2A Q03164 2/20 0.76
HSD17B10 Q99714 1/20 0.76
NPC1 O15118 2/20 0.62
RAB9A P51151 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
MLYCD O95822 1/20 0.62
HPGD P15428 4/20 0.60
NPSR1 Q6W5P4 1/20 0.60
GPR139 Q6DWJ6 1/20 0.58
ALDH1A1 P00352 2/20 0.56
MEN1 O00255 1/20 0.56
MAPT P10636 1/20 0.56
LMNA P02545 1/20 0.55
POLB P06746 1/20 0.55
EPHX2 P34913 1/20 0.53
KDM4E B2RXH2 1/20 0.53
NAAA Q02083 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4046696 0.94 KMT2A (0.69) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL11652211 0.93 KMT2A (0.67) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL17865783 0.90 MLYCD (0.73) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL18082335 0.89 NPC1 (0.71) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL14197819 0.88 GPR139 (0.68) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL27386734 0.86 NPC1 (0.61) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL3377096 0.86 NPC1 (0.66) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL8507006 0.86 NPC1 (0.66) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL8506869 0.86 NPC1 (0.66) GAAKMT2AHSD17B10NPC1RAB9A
SCHEMBL16105693 0.85 KMT2A (0.67) GAAKMT2AHSD17B10NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043327-A FGFR inhibitors and methods of use thereof 思康睿奇(上海)药业有限公司 2024-05-14 CN claimed
CN-111423396-B sEH inhibitor, and preparation method and application thereof 沈阳药科大学 2023-01-06 CN claimed
EP-3911645-B1 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE UNIV LILLE (FR) 2022-12-07 EP claimed
CN-108473429-B ROR gamma modulators 领先制药控股公司 2021-09-10 CN claimed
US-11015180-B2 Carboxyesterase polypeptides for amide coupling CODEXIS, INC. (US) 2021-05-25 US claimed
CN-112028928-A Cosmetic containing phytic acid amide salt 青岛姿之妍化妆品科技有限责任公司 2020-12-04 CN claimed
EP-3724325-A1 CARBOXYESTERASE POLYPEPTIDES FOR AMIDE COUPLING Codexis, Inc. (US) 2020-10-21 EP claimed
CN-111699250-A Carboxyesterase polypeptides for amide coupling 科德克希思公司 2020-09-22 CN claimed
WO-2019118557-A1 CARBOXYESTERASE POLYPEPTIDES FOR AMIDE COUPLING CODEXIS, INC. (US) 2019-06-20 WO claimed
US-20190177707-A1 CARBOXYESTERASE POLYPEPTIDES FOR AMIDE COUPLING INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2019-06-13 US claimed
EP-3303291-A1 ROR GAMMA (ROR ) MODULATORS Lead Pharma Holding B.V. (NL) 2018-04-11 EP claimed
WO-2016193452-A1 ROR GAMMA (RORγ) MODULATORS LEAD PHARMA CEL MODELS IP B.V. (NL) 2016-12-08 WO claimed
WO-2013007663-A1 2-BENZYLSULFANYL[1,3,4]-OXADIAZOLE DERIVATIVES, AND MEDICAL USE THEREOF Technische Universität Darmstadt (DE) 2013-01-17 WO claimed
EP-2032141-A1 INHIBITORS OF JANUS KINASES Merck & Co., Inc. (US) 2009-03-11 EP claimed
WO-2008107677-A2 THIADIAZOLE AND OXADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS SENEXIS LIMITED (GB) 2008-09-12 WO claimed
WO-2007145957-A1 INHIBITORS OF JANUS KINASES MERCK & CO., INC. (US) 2007-12-21 WO claimed
EP-1370260-A2 AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-12-17 EP claimed
WO-2002066035-A2 AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2002-08-29 WO claimed
US-20260014115-A1 SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS OREGON STATE UNIVERSITY (US) 2026-01-15 US disclosed
EP-0339976-A1 Anti-tumour agents IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014115-A1 SMALL MOLECULE BCL-2 FUNCTIONAL CONVERTERS AS CANCER THERAPEUTICS BCL2, BAX, BCL2A1 GAA 4848/4885KMT2A 3281/4885HSD17B10 2046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.