Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6387340 | 0.81 | ALDH1A1 (0.40) | GAASMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL2878428 | 0.79 | TSHR (0.45) | SMN1; SMN2ALDH1A1HPGDMAPTPRKDC | |
| SCHEMBL4626526 | 0.78 | HPGD (0.54) | GAASMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL6847147 | 0.71 | HPGD (0.47) | GAASMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| Benzophenone SCHEMBL9306548 | 0.70 | ALDH1A1 (0.70) | GAASMN1; SMN2ALDH1A1HPGDMAPT | |
| Fluoride SCHEMBL28319246 | 0.70 | AKR1C3 (0.81) | GAASMN1; SMN2ALDH1A1AKR1C3CYP2C9 | |
| SCHEMBL6620717 | 0.70 | RAB9A (0.41) | GAASMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29447165 | 0.68 | AKR1C3 (0.85) | GAAALDH1A1AKR1C3CYP2C9MAPT | |
| SCHEMBL700595 | 0.68 | AKR1C3 (0.85) | GAAALDH1A1AKR1C3CYP2C9MAPT | |
| Benzophenone SCHEMBL9305504 | 0.67 | ALDH1A1 (0.64) | GAASMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434557-A1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | claimed |
| WO-2003030845-A1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |