SCHEMBL4626526

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6847147	0.92	HPGD (0.47)	HPGDMAPTCYP1A2CYP2C9NPSR1
	SCHEMBL6848106	0.86	HPGD (0.42)	HPGDMAPTCYP1A2CYP2C9NPSR1
	SCHEMBL4625538	0.83	KDM4E (0.45)	HPGDMAPTCYP1A2CYP2C9ALDH1A1
	SCHEMBL15293601	0.80	CYP1A2 (0.43)	HPGDMAPTCYP1A2CYP2C9ALDH1A1
	SCHEMBL6656475	0.78	GAA (0.52)	HPGDMAPTCYP1A2CYP2C9NPSR1
	Benzophenone SCHEMBL9306548	0.76	ALDH1A1 (0.70)	HPGDMAPTNPSR1ALDH1A1MEN1
	Nitric Acid SCHEMBL8345678	0.75	MAPK1 (0.45)	MAPTALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL7048424	0.74	ALDH1A1 (0.40)	MAPTCYP1A2CYP2C9ALDH1A1KMT2A
	SCHEMBL320253	0.73	HPGD (0.49)	HPGDMAPTCYP1A2CYP2C9NPSR1
	Benzophenone SCHEMBL9305504	0.73	ALDH1A1 (0.64)	HPGDMAPTNPSR1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.