Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967080 | 0.92 | HSD11B1 (0.39) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL545781 | 0.89 | HSD11B1 (0.38) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL1573977 | 0.88 | CA1 (0.43) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL4964033 | 0.87 | HDAC1 (0.39) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL4962467 | 0.86 | CA1 (0.45) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL4964420 | 0.86 | CA1 (0.45) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL4962506 | 0.86 | CA1 (0.45) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL4962907 | 0.86 | CA1 (0.45) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL14674381 | 0.85 | HSD11B1 (0.40) | HSD11B1GAAL3MBTL1TSHRPOLB | |
| SCHEMBL107134 | 0.85 | CES1 (0.42) | HSD11B1GAAL3MBTL1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434091-A1 | CHEMICAL-AMPLIFICATION-TYPE POSITIVE RADIATION-SENSITIVE RESIN COMPOSITION | Clariant International Ltd. (CH) | 2004-06-30 | — | — | EP | disclosed |
| US-20040033438-A1 | Chemical-amplication-type positive radiation-sensitive resin composition | AZ ELECTRONIC MATERIALS USA CORP. | 2004-02-19 | — | — | US | disclosed |