Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9969418 | 0.84 | GSR (0.56) | GSREPHX2NR1H4MMP2MMP9 | |
| SCHEMBL6656619 | 0.79 | HSD17B3 (0.50) | LMNA | |
| SCHEMBL15556865 | 0.77 | GSR (0.59) | GSRMMP2MMP9MMP8GRIN2B | |
| SCHEMBL23064499 | 0.77 | MAPT (0.50) | LMNA | |
| SCHEMBL1327005 | 0.76 | GSR (0.63) | GSRMMP2MMP9MMP8GRIN2B | |
| Hydrochloric Acid SCHEMBL15465891 | 0.75 | GSR (0.60) | GSRMMP2MMP9MMP8GRIN2B | |
| SCHEMBL5058142 | 0.74 | GSR (0.61) | GSRMMP2MMP9MMP8ENPP2 | |
| SCHEMBL1185872 | 0.74 | GSR (0.61) | GSRMMP2MMP9MMP8ENPP2 | |
| SCHEMBL1381443 | 0.74 | CA2 (0.65) | GSRGRIN2BENPP2AKR1C3 | |
| SCHEMBL6755686 | 0.73 | MAOB (0.44) | GSREPHX2NR1H4ENPP2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061134-A9 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARM (GB) | 2004-04-22 | — | — | WO | disclosed |
| EP-1169031-A1 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000061134-A1 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |